node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AHN27935.1 | AHN29004.1 | SALWKB2_0553 | SALWKB2_1622 | Phosphoserine phosphatase. | Serine acetyltransferase. | 0.821 |
AHN27935.1 | AHN29069.1 | SALWKB2_0553 | SALWKB2_1687 | Phosphoserine phosphatase. | CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.901 |
AHN27935.1 | AHN29151.1 | SALWKB2_0553 | SALWKB2_1769 | Phosphoserine phosphatase. | Serine acetyltransferase. | 0.821 |
AHN27935.1 | glyA | SALWKB2_0553 | SALWKB2_0598 | Phosphoserine phosphatase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.922 |
AHN27935.1 | ilvA | SALWKB2_0553 | SALWKB2_0822 | Phosphoserine phosphatase. | Threonine dehydratase biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.910 |
AHN27935.1 | trpA | SALWKB2_0553 | SALWKB2_1812 | Phosphoserine phosphatase. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.901 |
AHN27935.1 | trpB | SALWKB2_0553 | SALWKB2_1817 | Phosphoserine phosphatase. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.911 |
AHN28407.1 | AHN29004.1 | SALWKB2_1025 | SALWKB2_1622 | Homoserine dehydrogenase. | Serine acetyltransferase. | 0.805 |
AHN28407.1 | AHN29151.1 | SALWKB2_1025 | SALWKB2_1769 | Homoserine dehydrogenase. | Serine acetyltransferase. | 0.805 |
AHN28407.1 | ilvA | SALWKB2_1025 | SALWKB2_0822 | Homoserine dehydrogenase. | Threonine dehydratase biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.503 |
AHN28407.1 | thrB | SALWKB2_1025 | SALWKB2_0065 | Homoserine dehydrogenase. | Homoserine kinase; Belongs to the pseudomonas-type ThrB family. | 0.928 |
AHN28657.1 | AHN29004.1 | SALWKB2_1275 | SALWKB2_1622 | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Serine acetyltransferase. | 0.985 |
AHN28657.1 | AHN29151.1 | SALWKB2_1275 | SALWKB2_1769 | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Serine acetyltransferase. | 0.993 |
AHN29004.1 | AHN27935.1 | SALWKB2_1622 | SALWKB2_0553 | Serine acetyltransferase. | Phosphoserine phosphatase. | 0.821 |
AHN29004.1 | AHN28407.1 | SALWKB2_1622 | SALWKB2_1025 | Serine acetyltransferase. | Homoserine dehydrogenase. | 0.805 |
AHN29004.1 | AHN28657.1 | SALWKB2_1622 | SALWKB2_1275 | Serine acetyltransferase. | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.985 |
AHN29004.1 | AHN29069.1 | SALWKB2_1622 | SALWKB2_1687 | Serine acetyltransferase. | CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.800 |
AHN29004.1 | AHN29151.1 | SALWKB2_1622 | SALWKB2_1769 | Serine acetyltransferase. | Serine acetyltransferase. | 0.924 |
AHN29004.1 | glyA | SALWKB2_1622 | SALWKB2_0598 | Serine acetyltransferase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.820 |
AHN29004.1 | ilvA | SALWKB2_1622 | SALWKB2_0822 | Serine acetyltransferase. | Threonine dehydratase biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.802 |