AHN24664.1 protein (Gilliamella apicola) - STRING interaction network

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Experiments

Co-purification, co-crystallization, Yeast2Hybrid, Genetic Interactions, etc ... as imported from primary sources.

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Cooccurrence

Gene families whose occurrence patterns across genomes show similarities.

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Databases

Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.

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Fusion

Genes that are sometimes fused into single open reading frames.

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Textmining

Automated, unsupervised textmining - searching for proteins that are frequently mentioned together.

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Coexpression

Proteins whose genes are observed to be correlated in expression, across a large number of experiments.

STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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[Homology]

Score

AHN24664.1

Hypothetical protein. (44 aa)

Predicted Functional Partners:

AHN24663.1

Hypothetical protein.

0.608

AHN24662.1

Hypothetical protein.

0.475

Your Current Organism:

Gilliamella apicola

NCBI taxonomy Id: 1196095
Other names: ATCC BAA-2448, Candidatus Gilliamella apicola, G. apicola, Gilliamella apicola Kwong and Moran 2013, NCIMB 14804, strain wkB1

Basic Settings

Network type:

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meaning of network edges:

evidence

( line color indicates the type of interaction evidence )

confidence

( line thickness indicates the strength of data support )

active interaction sources:

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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MFA: multi-fasta format - containing the aminoacid sequences in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AHN24662.1	AHN24663.1	GAPWK_0083	GAPWK_0084	Hypothetical protein.	Hypothetical protein.	0.594
AHN24662.1	AHN24664.1	GAPWK_0083	GAPWK_0085	Hypothetical protein.	Hypothetical protein.	0.475
AHN24663.1	AHN24662.1	GAPWK_0084	GAPWK_0083	Hypothetical protein.	Hypothetical protein.	0.594
AHN24663.1	AHN24664.1	GAPWK_0084	GAPWK_0085	Hypothetical protein.	Hypothetical protein.	0.608
AHN24664.1	AHN24662.1	GAPWK_0085	GAPWK_0083	Hypothetical protein.	Hypothetical protein.	0.475
AHN24664.1	AHN24663.1	GAPWK_0085	GAPWK_0084	Hypothetical protein.	Hypothetical protein.	0.608

[ The below analysis is limited to the network nodes included in the specified statistical background ]

Network Stats

number of nodes:

number of edges:

average node degree:

4.25

avg. local clustering coefficient:

0.935

expected number of edges:

PPI enrichment p-value:

0.00135

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
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Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:3874

Mixed, incl. Methyltransferase domain 25, and Ammonia-lyase activity

6 of 11

2.35

5.2

1.49e-10

CL:3876

Methyltransferase domain 25, and Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

5 of 5

2.61

5.02

1.66e-09

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