STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pflAPyruvate formate-lyase activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. (258 aa)    
Predicted Functional Partners:
pflB
Pyruvate formate-lyase.
  
 0.979
AHN25103.1
Formate efflux transporter; TC 2.A.44 family.
    
 0.805
AHN25195.1
Pyruvate formate-lyase.
  
 0.796
grcA
Pyruvate formate-lyase; Acts as a radical domain for damaged PFL and possibly other radical proteins.
  
     0.775
AHN24961.1
Alcohol dehydrogenase; Acetaldehyde dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
 
  
 0.774
AHN25197.1
Pyruvate formate-lyase.
  
  
 0.510
AHN25199.1
Pyruvate formate-lyase.
  
  
 0.510
AHN26458.1
Hypothetical protein.
  
  
 0.507
nifJ
Pyruvate-flavodoxin oxidoreductase.
     
 0.502
Your Current Organism:
Gilliamella apicola
NCBI taxonomy Id: 1196095
Other names: ATCC BAA-2448, Candidatus Gilliamella apicola, G. apicola, Gilliamella apicola Kwong and Moran 2013, NCIMB 14804, strain wkB1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.