STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHN25488.1HTH-type transcriptional regulator IlvY; Belongs to the LysR transcriptional regulatory family. (311 aa)    
Predicted Functional Partners:
AHN25824.1
Transcriptional regulator, LysR family protein; Belongs to the LysR transcriptional regulatory family.
  
     0.667
AHN25881.1
Transcriptional regulator, LysR family.
  
     0.629
AHN26544.1
Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.628
AHN25891.1
Transcriptional regulator, LysR family.
  
     0.622
AHN26320.1
DNA-binding transcriptional activator of the allD operon; Belongs to the LysR transcriptional regulatory family.
  
     0.595
AHN25487.1
Hypothetical protein.
       0.550
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
  
  
 0.504
prfC
Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
  
  
 0.500
AHN25890.1
Transcriptional regulator, LysR family.
  
     0.490
AHN24980.1
Glutamate synthase [NADPH] large chain.
  
  
 0.457
Your Current Organism:
Gilliamella apicola
NCBI taxonomy Id: 1196095
Other names: ATCC BAA-2448, Candidatus Gilliamella apicola, G. apicola, Gilliamella apicola Kwong and Moran 2013, NCIMB 14804, strain wkB1
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