AHN25580.1 protein (Gilliamella apicola) - STRING interaction network

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second shell of interactors

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a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

AHN25580.1

TonB-dependent receptor. (715 aa)

Predicted Functional Partners:

AHN26986.1

0.709

AHN27046.1

0.701

AHN26175.1

0.635

AHN26461.1

0.602

AHN26915.1

0.602

mltG

0.555

AHN25648.1

0.511

AHN25182.1

0.490

AHN25980.1

0.490

AHN25581.1

0.488

Your Current Organism:

Gilliamella apicola

NCBI taxonomy Id: 1196095
Other names: ATCC BAA-2448, Candidatus Gilliamella apicola, G. apicola, Gilliamella apicola Kwong and Moran 2013, NCIMB 14804, strain wkB1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AHN25182.1	AHN25580.1	GAPWK_0605	GAPWK_1003	Ferric vulnibactin receptor VuuA.	TonB-dependent receptor.	0.490
AHN25182.1	AHN26175.1	GAPWK_0605	GAPWK_1602	Ferric vulnibactin receptor VuuA.	Nonribosomal peptide synthetase.	0.465
AHN25182.1	AHN26986.1	GAPWK_0605	GAPWK_2413	Ferric vulnibactin receptor VuuA.	Ferrichrome-iron receptor.	0.408
AHN25182.1	AHN27046.1	GAPWK_0605	GAPWK_2473	Ferric vulnibactin receptor VuuA.	Hypothetical protein.	0.767
AHN25580.1	AHN25182.1	GAPWK_1003	GAPWK_0605	TonB-dependent receptor.	Ferric vulnibactin receptor VuuA.	0.490
AHN25580.1	AHN25581.1	GAPWK_1003	GAPWK_1004	TonB-dependent receptor.	Alanine racemase.	0.488
AHN25580.1	AHN25648.1	GAPWK_1003	GAPWK_1071	TonB-dependent receptor.	Hemin ABC transporter, permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.	0.511
AHN25580.1	AHN25980.1	GAPWK_1003	GAPWK_1403	TonB-dependent receptor.	Ferric vibriobactin receptor ViuA.	0.490
AHN25580.1	AHN26175.1	GAPWK_1003	GAPWK_1602	TonB-dependent receptor.	Nonribosomal peptide synthetase.	0.635
AHN25580.1	AHN26461.1	GAPWK_1003	GAPWK_1888	TonB-dependent receptor.	Hypothetical protein.	0.602
AHN25580.1	AHN26915.1	GAPWK_1003	GAPWK_2342	TonB-dependent receptor.	Hypothetical protein.	0.602
AHN25580.1	AHN26986.1	GAPWK_1003	GAPWK_2413	TonB-dependent receptor.	Ferrichrome-iron receptor.	0.709
AHN25580.1	AHN27046.1	GAPWK_1003	GAPWK_2473	TonB-dependent receptor.	Hypothetical protein.	0.701
AHN25580.1	mltG	GAPWK_1003	GAPWK_1005	TonB-dependent receptor.	Protein YceG like; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.	0.555
AHN25581.1	AHN25580.1	GAPWK_1004	GAPWK_1003	Alanine racemase.	TonB-dependent receptor.	0.488
AHN25581.1	AHN26175.1	GAPWK_1004	GAPWK_1602	Alanine racemase.	Nonribosomal peptide synthetase.	0.464
AHN25581.1	mltG	GAPWK_1004	GAPWK_1005	Alanine racemase.	Protein YceG like; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.	0.815
AHN25648.1	AHN25580.1	GAPWK_1071	GAPWK_1003	Hemin ABC transporter, permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.	TonB-dependent receptor.	0.511
AHN25648.1	AHN26175.1	GAPWK_1071	GAPWK_1602	Hemin ABC transporter, permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.	Nonribosomal peptide synthetase.	0.556
AHN25648.1	AHN26986.1	GAPWK_1071	GAPWK_2413	Hemin ABC transporter, permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.	Ferrichrome-iron receptor.	0.430

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Network Stats

number of nodes:

11

number of edges:

32

average node degree:

5.82

avg. local clustering coefficient:

0.954

expected number of edges:

15

PPI enrichment p-value:

0.00012

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0019637

Organophosphate metabolic process

8 of 166

1.2

1.58

1.71e-07

GO:0019563

Glycerol catabolic process

2 of 2

2.52

1.58

0.0012

GO:0006072

glycerol-3-phosphate metabolic process

2 of 3

2.34

1.46

0.0019

GO:1901135

Carbohydrate derivative metabolic process

8 of 190

1.15

1.43

4.22e-07

GO:0006796

Phosphate-containing compound metabolic process

10 of 278

1.08

1.39

1.11e-08

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0046933

Proton-transporting ATP synthase activity, rotational mechanism

6 of 9

2.34

4.59

4.24e-10

GO:0004370

Glycerol kinase activity

2 of 2

2.52

1.57

0.0013

GO:0046961

Proton-transporting ATPase activity, rotational mechanism

2 of 3

2.34

1.44

0.0021

GO:0005524

ATP binding

7 of 331

0.85

0.72

0.00061

GO:0043167

Ion binding

8 of 721

0.57

0.43

0.0043

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0045259

Proton-transporting ATP synthase complex

6 of 8

2.4

5.06

5.11e-11

GO:0045261

Proton-transporting ATP synthase complex, catalytic core F(1)

5 of 5

2.52

4.64

8.73e-10

GO:0032991

Protein-containing complex

7 of 184

1.1

1.24

5.38e-06

GO:0005622

Intracellular anatomical structure

11 of 988

0.57

0.51

1.06e-05

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:380

ATP synthesis

6 of 8

2.4

4.73

2.92e-10

CL:219

Ribosome, and Regulation of translation

7 of 89

1.42

1.93

7.33e-07

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00190

Oxidative phosphorylation

7 of 55

1.63

2.75

1.08e-08

map00561

Glycerolipid metabolism

3 of 13

1.88

1.56

0.00067

map01100

Metabolic pathways

9 of 1186

0.4

0.27

0.0461

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0045259

Proton-transporting ATP synthase complex

6 of 8

2.4

4.91

1.15e-10

GOCC:0045261

Proton-transporting ATP synthase complex, catalytic core F(1)

5 of 5

2.52

4.48

1.96e-09

GOCC:0005622

Intracellular

10 of 1221

0.43

0.34

0.0064

GOCC:0110165

Cellular anatomical entity

11 of 1919

0.28

0.23

0.0339

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0375

Hydrogen ion transport

6 of 8

2.4

4.97

8.03e-11

KW-0066

ATP synthesis

6 of 8

2.4

4.97

8.03e-11

KW-0139

CF(1)

5 of 5

2.52

4.61

1.03e-09

KW-1003

Cell membrane

6 of 127

1.2

1.31

2.65e-05

KW-1278

Translocase

2 of 15

1.65

0.76

0.0303

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF02874

ATP synthase alpha/beta family, beta-barrel domain

2 of 2

2.52

0.92

0.0211

PF02782

FGGY family of carbohydrate kinases, C-terminal domain

2 of 2

2.52

0.92

0.0211

PF00370

FGGY family of carbohydrate kinases, N-terminal domain

2 of 2

2.52

0.92

0.0211

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