STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
queDQueuosine biosynthesis QueD, PTPS-I. (142 aa)    
Predicted Functional Partners:
queE
Queuosine Biosynthesis QueE Radical SAM; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
 
 
 0.998
folE
GTP cyclohydrolase I type 1.
  
 
 0.978
queC
Queuosine Biosynthesis QueC ATPase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.
 
  
 0.975
AHN26964.1
Dihydroneopterin triphosphate pyrophosphohydrolase type 2 (nudB).
    
  0.903
queF
NADPH dependent preQ0 reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
 
  
 0.845
AHN24843.1
Ribonucleotide reductase of class III (anaerobic), activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
  
  
 0.693
AHN25216.1
Ribonucleotide reductase of class III (anaerobic), activating protein.
  
  
 0.693
cysS
Cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
  
 0.618
hisI
Phosphoribosyl-AMP cyclohydrolase / Phosphoribosyl-ATP pyrophosphatase; In the N-terminal section; belongs to the PRA-CH family.
     
 0.481
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
     
 0.457
Your Current Organism:
Gilliamella apicola
NCBI taxonomy Id: 1196095
Other names: ATCC BAA-2448, Candidatus Gilliamella apicola, G. apicola, Gilliamella apicola Kwong and Moran 2013, NCIMB 14804, strain wkB1
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