STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHN26591.1Sigma factor RpoE negative regulatory protein RseA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytop [...] (187 aa)    
Predicted Functional Partners:
AHN26590.1
Sigma factor RpoE negative regulatory protein RseB precursor.
 
 0.998
rpoE
RNA polymerase sigma factor RpoE; Belongs to the sigma-70 factor family. ECF subfamily.
 
 
 0.994
AHN25319.1
Putative RNA polymerase; Belongs to the sigma-70 factor family. ECF subfamily.
  
 
 0.872
ftsL
Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
  
 
   0.776
AHN25124.1
Uncharacterized protein YrbK; Clustered with lipopolysaccharide transporters.
  
     0.769
rraB
Ribonuclease E inhibitor RraB; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
  
     0.767
slyX
SlyX; Belongs to the SlyX family.
  
     0.762
AHN27065.1
Syd protein.
  
     0.758
AHN26773.1
Outer membrane stress sensor protease DegS.
  
 
 0.757
AHN26774.1
Outer membrane stress sensor protease DegQ, serine protease; Belongs to the peptidase S1C family.
  
 
 0.757
Your Current Organism:
Gilliamella apicola
NCBI taxonomy Id: 1196095
Other names: ATCC BAA-2448, Candidatus Gilliamella apicola, G. apicola, Gilliamella apicola Kwong and Moran 2013, NCIMB 14804, strain wkB1
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