node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AHN26404.1 | AHN26610.1 | GAPWK_1831 | GAPWK_2037 | SeqA protein, negative modulator of initiation of replication; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated; Belongs to the SeqA family. | Lipoprotein nlpI precursor. | 0.770 |
AHN26404.1 | AHN26618.1 | GAPWK_1831 | GAPWK_2045 | SeqA protein, negative modulator of initiation of replication; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated; Belongs to the SeqA family. | ProQ: influences osmotic activation of compatible solute ProP. | 0.777 |
AHN26404.1 | AHN26693.1 | GAPWK_1831 | GAPWK_2120 | SeqA protein, negative modulator of initiation of replication; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated; Belongs to the SeqA family. | Methyl-directed repair DNA adenine methylase. | 0.644 |
AHN26404.1 | metJ | GAPWK_1831 | GAPWK_2198 | SeqA protein, negative modulator of initiation of replication; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated; Belongs to the SeqA family. | Methionine repressor MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | 0.818 |
AHN26404.1 | mutH | GAPWK_1831 | GAPWK_0309 | SeqA protein, negative modulator of initiation of replication; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated; Belongs to the SeqA family. | DNA mismatch repair endonuclease MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair. Belongs to the MutH family. | 0.797 |
AHN26404.1 | rraB | GAPWK_1831 | GAPWK_0968 | SeqA protein, negative modulator of initiation of replication; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated; Belongs to the SeqA family. | Ribonuclease E inhibitor RraB; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | 0.774 |
AHN26610.1 | AHN26404.1 | GAPWK_2037 | GAPWK_1831 | Lipoprotein nlpI precursor. | SeqA protein, negative modulator of initiation of replication; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated; Belongs to the SeqA family. | 0.770 |
AHN26610.1 | AHN26618.1 | GAPWK_2037 | GAPWK_2045 | Lipoprotein nlpI precursor. | ProQ: influences osmotic activation of compatible solute ProP. | 0.784 |
AHN26610.1 | AHN26693.1 | GAPWK_2037 | GAPWK_2120 | Lipoprotein nlpI precursor. | Methyl-directed repair DNA adenine methylase. | 0.659 |
AHN26610.1 | metJ | GAPWK_2037 | GAPWK_2198 | Lipoprotein nlpI precursor. | Methionine repressor MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | 0.772 |
AHN26610.1 | mutH | GAPWK_2037 | GAPWK_0309 | Lipoprotein nlpI precursor. | DNA mismatch repair endonuclease MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair. Belongs to the MutH family. | 0.750 |
AHN26610.1 | rraB | GAPWK_2037 | GAPWK_0968 | Lipoprotein nlpI precursor. | Ribonuclease E inhibitor RraB; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | 0.775 |
AHN26618.1 | AHN26404.1 | GAPWK_2045 | GAPWK_1831 | ProQ: influences osmotic activation of compatible solute ProP. | SeqA protein, negative modulator of initiation of replication; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated; Belongs to the SeqA family. | 0.777 |
AHN26618.1 | AHN26610.1 | GAPWK_2045 | GAPWK_2037 | ProQ: influences osmotic activation of compatible solute ProP. | Lipoprotein nlpI precursor. | 0.784 |
AHN26618.1 | AHN26693.1 | GAPWK_2045 | GAPWK_2120 | ProQ: influences osmotic activation of compatible solute ProP. | Methyl-directed repair DNA adenine methylase. | 0.634 |
AHN26618.1 | metJ | GAPWK_2045 | GAPWK_2198 | ProQ: influences osmotic activation of compatible solute ProP. | Methionine repressor MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | 0.757 |
AHN26618.1 | mutH | GAPWK_2045 | GAPWK_0309 | ProQ: influences osmotic activation of compatible solute ProP. | DNA mismatch repair endonuclease MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair. Belongs to the MutH family. | 0.759 |
AHN26618.1 | rraB | GAPWK_2045 | GAPWK_0968 | ProQ: influences osmotic activation of compatible solute ProP. | Ribonuclease E inhibitor RraB; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | 0.774 |
AHN26692.1 | AHN26693.1 | GAPWK_2119 | GAPWK_2120 | DamX, an inner membrane protein involved in bile resistance. | Methyl-directed repair DNA adenine methylase. | 0.677 |
AHN26692.1 | AHN26694.1 | GAPWK_2119 | GAPWK_2121 | DamX, an inner membrane protein involved in bile resistance. | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | 0.529 |