STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A370_02906PFAM: tRNA (Uracil-5-)-methyltransferase; TIGRFAM: 23S rRNA (uracil-5-)-methyltransferase RumA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (454 aa)    
Predicted Functional Partners:
A370_02904
Hypothetical protein.
       0.683
A370_02903
PFAM: SLBB domain; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat region; comEA protein.
 
     0.648
A370_04285
rRNA methylase, putative, group 3; PFAM: SpoU rRNA Methylase family; RNA 2'-O ribose methyltransferase substrate binding; TIGRFAM: rRNA methylase, putative, group 3; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
 
  
 0.641
A370_03447
Ribosomal RNA small subunit methyltransferase RsmB; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
 
  
 0.635
A370_01402
PFAM: SpoU rRNA Methylase family; RNA 2'-O ribose methyltransferase substrate binding; TIGRFAM: rRNA methylase, putative, group 3; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
 
  
 0.616
trmB
tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
  
  
 0.593
A370_02905
Hypothetical protein.
       0.574
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
  
 0.536
rsmA
Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
   
  
 0.535
rnz
Ribonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family.
 
    0.526
Your Current Organism:
Clostridium sp. Maddingley
NCBI taxonomy Id: 1196322
Other names: C. sp. Maddingley MBC34-26, Clostridium sp. Maddingley MBC34-26
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.