STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDL75318.13-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (425 aa)    
Predicted Functional Partners:
SDN29006.1
Acyl transferase domain-containing protein.
  
0.999
SDM05619.1
Minimal PKS chain-length factor (CLF/KS beta); Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 
 
0.998
SDM78734.1
[acyl-carrier-protein] S-malonyltransferase.
 
 0.997
SDM79206.1
acetyl-CoA carboxylase carboxyl transferase subunit beta.
 
 
 0.997
fabH
3-oxoacyl-[acyl-carrier-protein] synthase-3; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
 
 0.992
fabH-2
3-oxoacyl-[acyl-carrier-protein] synthase-3; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
 
 0.992
SDL75116.1
Amino acid adenylation domain-containing protein.
 
 0.991
SDM01409.1
Amino acid adenylation domain-containing protein.
 
 0.980
SDM10253.1
3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 0.978
SDL75100.1
Ketoacyl-synthetase C-terminal extension.
 
0.976
Your Current Organism:
Streptomyces wuyuanensis
NCBI taxonomy Id: 1196353
Other names: CGMCC 4.7042, KCTC 29112, S. wuyuanensis, Streptomyces sp. FX61, Streptomyces wuyuanensis Zhang et al. 2013, strain FX61
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