STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WEN_00010COG0592 DNA polymerase sliding clamp subunit (PCNA homolog). (382 aa)    
Predicted Functional Partners:
WEN_00685
DNA polymerase I; COG0258 5'-3' exonuclease (including N-terminal domain of PolI).
  
 0.999
WEN_00690
COG0587 DNA polymerase III, alpha subunit.
    
 0.999
dnaX
DNA polymerase III subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
   
 0.999
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 0.987
WEN_02850
DNA helicase, UvrD type; COG0210 Superfamily I DNA and RNA helicases.
  
 
 0.982
recA
COG0468 RecA/RadA recombinase; Belongs to the RecA family.
  
 0.969
polC
DNA polymerase III polC-type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
   
 0.933
hrcA
Heat-inducible transcription repressor; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.
  
    0.844
WEN_00025
ABC transporter-like ATP-binding protein; COG1131 ABC-type multidrug transport system, ATPase component.
  
    0.829
WEN_00015
Membrane protein.
       0.800
Your Current Organism:
Mycoplasma wenyonii
NCBI taxonomy Id: 1197325
Other names: M. wenyonii str. Massachusetts, Mycoplasma wenyonii str. Massachusetts, Mycoplasma wenyonii strain Massachusetts
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