STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WEN_00375COG0776 Bacterial nucleoid DNA-binding protein; Belongs to the bacterial histone-like protein family. (95 aa)    
Predicted Functional Partners:
WEN_00370
Histone-like DNA-binding superfamily protein HimA; COG0776 Bacterial nucleoid DNA-binding protein; Belongs to the bacterial histone-like protein family.
      
0.806
WEN_00365
Hypothetical protein.
       0.770
WEN_00380
GTP-binding protein Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
   
   0.757
WEN_00385
COG0510 Predicted choline kinase involved in LPS biosynthesis.
       0.659
WEN_00390
H+transporting two-sector ATPase delta/subunit epsilon.
       0.647
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.641
WEN_00395
Hydrolase, TatD family protein; COG0084 Mg-dependent DNase.
       0.620
WEN_00685
DNA polymerase I; COG0258 5'-3' exonuclease (including N-terminal domain of PolI).
   
 
 0.620
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.555
WEN_02585
30S ribosomal protein S15; Belongs to the universal ribosomal protein uS15 family.
  
  
 0.536
Your Current Organism:
Mycoplasma wenyonii
NCBI taxonomy Id: 1197325
Other names: M. wenyonii str. Massachusetts, Mycoplasma wenyonii str. Massachusetts, Mycoplasma wenyonii strain Massachusetts
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.