STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NEOLI_0015273-hydroxy-3-methylglutaryl-coenzyme A reductase. (979 aa)    
Predicted Functional Partners:
NEOLI_002939
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
  
 
 0.992
NEOLI_004977
Chromatin assembly factor 1 subunit rlf2.
   
 
 0.917
NEOLI_001528
ERAD-associated E3 ubiquitin-protein ligase HRD1.
   
 
 0.907
NEOLI_001145
Mevalonate kinase.
  
 0.900
NEOLI_000213
Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family.
  
 
 0.892
NEOLI_002375
Squalene monooxygenase.
   
  
 0.889
NEOLI_002968
Lanosterol 14-alpha demethylase erg11; Belongs to the cytochrome P450 family.
   
  
 0.874
NEOLI_000188
5'-AMP-activated protein kinase subunit gamma.
    
 0.796
NEOLI_002456
Sterol regulatory element-binding protein 1.
     
 0.754
NEOLI_003978
AMPKBI domain-containing protein.
     
 0.747
Your Current Organism:
Neolecta irregularis
NCBI taxonomy Id: 1198029
Other names: N. irregularis DAH-3, Neolecta irregularis DAH-3
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