node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FEN1 | NEOLI_000180 | A0A1U7LHW3 | A0A1U7LTL5 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | N-acetyltransferase eso1. | 0.804 |
FEN1 | NEOLI_001493 | A0A1U7LHW3 | A0A1U7LQJ1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA polymerase subunit delta-2. | 0.975 |
FEN1 | NEOLI_002687 | A0A1U7LHW3 | A0A1U7LXB9 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Werner syndrome ATP-dependent helicase. | 0.996 |
FEN1 | NEOLI_002742 | A0A1U7LHW3 | A0A1U7LWA8 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Replication factor C subunit 2. | 0.901 |
FEN1 | NEOLI_003074 | A0A1U7LHW3 | A0A1U7LJB5 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Uncharacterized protein. | 0.770 |
FEN1 | NEOLI_003133 | A0A1U7LHW3 | A0A1U7LMX6 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.981 |
FEN1 | NEOLI_003899 | A0A1U7LHW3 | A0A1U7LHT7 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA ligase. | 0.984 |
FEN1 | NEOLI_004105 | A0A1U7LHW3 | A0A1U7LSD6 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Replication factor C subunit 5. | 0.906 |
FEN1 | NEOLI_004149 | A0A1U7LHW3 | A0A1U7LMA0 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA mismatch repair protein msh6; Component of the post-replicative DNA mismatch repair system (MMR). | 0.930 |
FEN1 | NEOLI_004393 | A0A1U7LHW3 | A0A1U7LPL7 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA polymerase; Belongs to the universal ribosomal protein uS8 family. | 0.986 |
NEOLI_000180 | FEN1 | A0A1U7LTL5 | A0A1U7LHW3 | N-acetyltransferase eso1. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.804 |
NEOLI_000180 | NEOLI_001493 | A0A1U7LTL5 | A0A1U7LQJ1 | N-acetyltransferase eso1. | DNA polymerase subunit delta-2. | 0.822 |
NEOLI_000180 | NEOLI_002687 | A0A1U7LTL5 | A0A1U7LXB9 | N-acetyltransferase eso1. | Werner syndrome ATP-dependent helicase. | 0.969 |
NEOLI_000180 | NEOLI_002742 | A0A1U7LTL5 | A0A1U7LWA8 | N-acetyltransferase eso1. | Replication factor C subunit 2. | 0.980 |
NEOLI_000180 | NEOLI_003074 | A0A1U7LTL5 | A0A1U7LJB5 | N-acetyltransferase eso1. | Uncharacterized protein. | 0.804 |
NEOLI_000180 | NEOLI_003133 | A0A1U7LTL5 | A0A1U7LMX6 | N-acetyltransferase eso1. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.999 |
NEOLI_000180 | NEOLI_003899 | A0A1U7LTL5 | A0A1U7LHT7 | N-acetyltransferase eso1. | DNA ligase. | 0.785 |
NEOLI_000180 | NEOLI_004105 | A0A1U7LTL5 | A0A1U7LSD6 | N-acetyltransferase eso1. | Replication factor C subunit 5. | 0.976 |
NEOLI_000180 | NEOLI_004149 | A0A1U7LTL5 | A0A1U7LMA0 | N-acetyltransferase eso1. | DNA mismatch repair protein msh6; Component of the post-replicative DNA mismatch repair system (MMR). | 0.557 |
NEOLI_000180 | NEOLI_004393 | A0A1U7LTL5 | A0A1U7LPL7 | N-acetyltransferase eso1. | DNA polymerase; Belongs to the universal ribosomal protein uS8 family. | 0.962 |