STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NEOLI_003133Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (827 aa)    
Predicted Functional Partners:
NEOLI_000180
N-acetyltransferase eso1.
   
 0.999
NEOLI_002687
Werner syndrome ATP-dependent helicase.
  
 0.991
NEOLI_002742
Replication factor C subunit 2.
  
 0.989
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
   
 0.981
NEOLI_004105
Replication factor C subunit 5.
  
 0.976
NEOLI_003899
DNA ligase.
   
 0.975
NEOLI_004149
DNA mismatch repair protein msh6; Component of the post-replicative DNA mismatch repair system (MMR).
   
 0.975
NEOLI_003074
Uncharacterized protein.
   
 0.969
NEOLI_004393
DNA polymerase; Belongs to the universal ribosomal protein uS8 family.
  
 0.969
NEOLI_001493
DNA polymerase subunit delta-2.
   
 0.967
Your Current Organism:
Neolecta irregularis
NCBI taxonomy Id: 1198029
Other names: N. irregularis DAH-3, Neolecta irregularis DAH-3
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