node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FEN1 | NEOLI_000058 | A0A1U7LHW3 | A0A1U7LV99 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA polymerase alpha catalytic subunit. | 0.889 |
FEN1 | NEOLI_000059 | A0A1U7LHW3 | A0A1U7LVC1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA polymerase. | 0.889 |
FEN1 | NEOLI_001493 | A0A1U7LHW3 | A0A1U7LQJ1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA polymerase subunit delta-2. | 0.975 |
FEN1 | NEOLI_002099 | A0A1U7LHW3 | A0A1U7LTV4 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. | 0.900 |
FEN1 | NEOLI_002427 | A0A1U7LHW3 | A0A1U7LHI4 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA polymerase zeta catalytic subunit. | 0.847 |
FEN1 | NEOLI_002687 | A0A1U7LHW3 | A0A1U7LXB9 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Werner syndrome ATP-dependent helicase. | 0.996 |
FEN1 | NEOLI_003133 | A0A1U7LHW3 | A0A1U7LMX6 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.981 |
FEN1 | NEOLI_003455 | A0A1U7LHW3 | A0A1U7LHY0 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Vezatin domain-containing protein. | 0.981 |
FEN1 | NEOLI_004393 | A0A1U7LHW3 | A0A1U7LPL7 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA polymerase; Belongs to the universal ribosomal protein uS8 family. | 0.986 |
NEOLI_000058 | FEN1 | A0A1U7LV99 | A0A1U7LHW3 | DNA polymerase alpha catalytic subunit. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.889 |
NEOLI_000058 | NEOLI_000059 | A0A1U7LV99 | A0A1U7LVC1 | DNA polymerase alpha catalytic subunit. | DNA polymerase. | 0.899 |
NEOLI_000058 | NEOLI_001493 | A0A1U7LV99 | A0A1U7LQJ1 | DNA polymerase alpha catalytic subunit. | DNA polymerase subunit delta-2. | 0.961 |
NEOLI_000058 | NEOLI_002099 | A0A1U7LV99 | A0A1U7LTV4 | DNA polymerase alpha catalytic subunit. | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. | 0.964 |
NEOLI_000058 | NEOLI_002248 | A0A1U7LV99 | A0A1U7LTE7 | DNA polymerase alpha catalytic subunit. | DNA polymerase zeta processivity subunit. | 0.940 |
NEOLI_000058 | NEOLI_002427 | A0A1U7LV99 | A0A1U7LHI4 | DNA polymerase alpha catalytic subunit. | DNA polymerase zeta catalytic subunit. | 0.456 |
NEOLI_000058 | NEOLI_002687 | A0A1U7LV99 | A0A1U7LXB9 | DNA polymerase alpha catalytic subunit. | Werner syndrome ATP-dependent helicase. | 0.837 |
NEOLI_000058 | NEOLI_003133 | A0A1U7LV99 | A0A1U7LMX6 | DNA polymerase alpha catalytic subunit. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.921 |
NEOLI_000058 | NEOLI_003455 | A0A1U7LV99 | A0A1U7LHY0 | DNA polymerase alpha catalytic subunit. | Vezatin domain-containing protein. | 0.921 |
NEOLI_000058 | NEOLI_004393 | A0A1U7LV99 | A0A1U7LPL7 | DNA polymerase alpha catalytic subunit. | DNA polymerase; Belongs to the universal ribosomal protein uS8 family. | 0.879 |
NEOLI_000059 | FEN1 | A0A1U7LVC1 | A0A1U7LHW3 | DNA polymerase. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.889 |