NEOLI_002829 protein (Neolecta irregularis) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:

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Score

NEOLI_002829

Periplasmic beta-glucosidase. (783 aa)

Predicted Functional Partners:

NEOLI_004198

0.823

NEOLI_004609

0.812

NEOLI_001761

0.811

NEOLI_004587

0.806

NEOLI_001227

0.792

NEOLI_000068

0.780

NEOLI_004741

0.770

NEOLI_000515

0.770

NEOLI_001908

0.748

NEOLI_001798

0.728

Your Current Organism:

Neolecta irregularis

NCBI taxonomy Id: 1198029
Other names: N. irregularis DAH-3, Neolecta irregularis DAH-3

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NEOLI_000068	NEOLI_001761	A0A1U7LVA8	A0A1U7LWD6	40S ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family.	Putative family 31 glucosidase; Belongs to the glycosyl hydrolase 31 family.	0.465
NEOLI_000068	NEOLI_002829	A0A1U7LVA8	A0A1U7LSJ7	40S ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family.	Periplasmic beta-glucosidase.	0.780
NEOLI_000068	NEOLI_004198	A0A1U7LVA8	A0A1U7LRJ0	40S ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family.	Beta-glucosidase; Belongs to the glycosyl hydrolase 3 family.	0.780
NEOLI_000068	NEOLI_004609	A0A1U7LVA8	A0A1U7LL39	40S ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family.	Putative endo-beta-1,4-glucanase B; Belongs to the glycosyl hydrolase 5 (cellulase A) family.	0.465
NEOLI_000515	NEOLI_001798	A0A1U7LS15	A0A1U7LH53	Calmodulin; Belongs to the calmodulin family.	Myosin regulatory light chain 1.	0.855
NEOLI_000515	NEOLI_002829	A0A1U7LS15	A0A1U7LSJ7	Calmodulin; Belongs to the calmodulin family.	Periplasmic beta-glucosidase.	0.770
NEOLI_000515	NEOLI_004198	A0A1U7LS15	A0A1U7LRJ0	Calmodulin; Belongs to the calmodulin family.	Beta-glucosidase; Belongs to the glycosyl hydrolase 3 family.	0.770
NEOLI_000515	NEOLI_004741	A0A1U7LS15	A0A1U7LLL7	Calmodulin; Belongs to the calmodulin family.	Myosin regulatory light chain cdc4 isoform A.	0.936
NEOLI_001227	NEOLI_002829	A0A1U7LK97	A0A1U7LSJ7	Pre-rRNA-processing protein IPI3.	Periplasmic beta-glucosidase.	0.792
NEOLI_001227	NEOLI_004198	A0A1U7LK97	A0A1U7LRJ0	Pre-rRNA-processing protein IPI3.	Beta-glucosidase; Belongs to the glycosyl hydrolase 3 family.	0.792
NEOLI_001761	NEOLI_000068	A0A1U7LWD6	A0A1U7LVA8	Putative family 31 glucosidase; Belongs to the glycosyl hydrolase 31 family.	40S ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family.	0.465
NEOLI_001761	NEOLI_001908	A0A1U7LWD6	A0A1U7LPU9	Putative family 31 glucosidase; Belongs to the glycosyl hydrolase 31 family.	Uncharacterized protein.	0.537
NEOLI_001761	NEOLI_002829	A0A1U7LWD6	A0A1U7LSJ7	Putative family 31 glucosidase; Belongs to the glycosyl hydrolase 31 family.	Periplasmic beta-glucosidase.	0.811
NEOLI_001761	NEOLI_004198	A0A1U7LWD6	A0A1U7LRJ0	Putative family 31 glucosidase; Belongs to the glycosyl hydrolase 31 family.	Beta-glucosidase; Belongs to the glycosyl hydrolase 3 family.	0.820
NEOLI_001798	NEOLI_000515	A0A1U7LH53	A0A1U7LS15	Myosin regulatory light chain 1.	Calmodulin; Belongs to the calmodulin family.	0.855
NEOLI_001798	NEOLI_002829	A0A1U7LH53	A0A1U7LSJ7	Myosin regulatory light chain 1.	Periplasmic beta-glucosidase.	0.728
NEOLI_001798	NEOLI_004198	A0A1U7LH53	A0A1U7LRJ0	Myosin regulatory light chain 1.	Beta-glucosidase; Belongs to the glycosyl hydrolase 3 family.	0.728
NEOLI_001798	NEOLI_004741	A0A1U7LH53	A0A1U7LLL7	Myosin regulatory light chain 1.	Myosin regulatory light chain cdc4 isoform A.	0.885
NEOLI_001908	NEOLI_001761	A0A1U7LPU9	A0A1U7LWD6	Uncharacterized protein.	Putative family 31 glucosidase; Belongs to the glycosyl hydrolase 31 family.	0.537
NEOLI_001908	NEOLI_002829	A0A1U7LPU9	A0A1U7LSJ7	Uncharacterized protein.	Periplasmic beta-glucosidase.	0.748

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Network Stats

number of nodes:

11

number of edges:

15

average node degree:

2.73

avg. local clustering coefficient:

0.919

expected number of edges:

11

PPI enrichment p-value:

0.145

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:1901607

Alpha-amino acid biosynthetic process

9 of 97

1.48

2.54

8.52e-10

GO:0006566

Threonine metabolic process

3 of 11

1.94

1.68

0.00040

GO:0044283

Small molecule biosynthetic process

10 of 217

1.17

1.64

3.96e-09

GO:0009070

Serine family amino acid biosynthetic process

3 of 16

1.78

1.45

0.00094

GO:0006563

L-serine metabolic process

2 of 8

1.91

0.97

0.0132

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004834

Tryptophan synthase activity

3 of 3

2.51

1.9

0.00030

GO:0016841

Ammonia-lyase activity

3 of 5

2.29

1.86

0.00030

GO:0030170

Pyridoxal phosphate binding

4 of 35

1.57

1.38

0.00066

GO:0004794

L-threonine ammonia-lyase activity

2 of 2

2.51

1.28

0.0044

GO:0016829

Lyase activity

6 of 116

1.22

1.16

0.00030

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1074

Glycine, serine and threonine metabolism

6 of 13

2.17

4.17

1.16e-09

CL:1073

Cysteine and methionine metabolism, and Pyridoxal-phosphate dependent enzyme

7 of 23

1.99

4.04

2.89e-10

CL:1070

Biosynthesis of amino acids

9 of 90

1.51

2.7

2.89e-10

CL:1076

Threonine biosynthesis, and Threonine synthase-like

2 of 6

2.03

0.83

0.0272

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

tbi00260

Glycine, serine and threonine metabolism

11 of 31

2.06

7.05

1.58e-20

tbi01230

Biosynthesis of amino acids

10 of 113

1.46

2.82

9.54e-13

tbi01110

Biosynthesis of secondary metabolites

11 of 301

1.07

1.48

7.03e-11

tbi01200

Carbon metabolism

5 of 85

1.28

1.34

7.99e-05

tbi00400

Phenylalanine, tyrosine and tryptophan biosynthesis

3 of 25

1.59

1.31

0.0012

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005829

Cytosol

8 of 401

0.81

0.66

0.0010

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0822

Tryptophan biosynthesis

3 of 6

2.21

1.94

0.00018

KW-0028

Amino-acid biosynthesis

5 of 61

1.42

1.44

0.00016

KW-0663

Pyridoxal phosphate

3 of 35

1.44

0.96

0.0069

KW-0456

Lyase

4 of 79

1.21

0.9

0.0040

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00291

Pyridoxal-phosphate dependent enzyme

5 of 8

2.3

3.58

6.80e-08

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR036052

Tryptophan synthase beta chain-like, PALP domain superfamily

5 of 8

2.3

3.39

1.84e-07

IPR001926

Tryptophan synthase beta chain-like, PALP domain

5 of 8

2.3

3.39

1.84e-07

IPR023026

Tryptophan synthase beta chain/beta chain-like

2 of 2

2.51

0.87

0.0257

IPR006654

Tryptophan synthase, beta chain

2 of 2

2.51

0.87

0.0257

IPR006653

Tryptophan synthase, beta chain, conserved site

2 of 2

2.51

0.87

0.0257

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