NEOLI_001350 protein (Neolecta irregularis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

NEOLI_001350

Putative pentatricopeptide repeat-containing protein. (623 aa)

Predicted Functional Partners:

NEOLI_001308

0.756

NEOLI_003692

0.743

NEOLI_003587

0.743

NEOLI_003295

0.743

NEOLI_004078

0.739

NEOLI_003565

0.734

NEOLI_002396

0.717

NEOLI_002832

0.671

NEOLI_001032

0.658

NEOLI_001412

0.641

Your Current Organism:

Neolecta irregularis

NCBI taxonomy Id: 1198029
Other names: N. irregularis DAH-3, Neolecta irregularis DAH-3

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NEOLI_001032	NEOLI_001350	A0A1U7LGN3	A0A1U7LVD4	Putative methylcrotonoyl-CoA carboxylase beta chain, mitochondrial.	Putative pentatricopeptide repeat-containing protein.	0.658
NEOLI_001308	NEOLI_001350	A0A1U7LKN5	A0A1U7LVD4	Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.	Putative pentatricopeptide repeat-containing protein.	0.756
NEOLI_001308	NEOLI_003295	A0A1U7LKN5	A0A1U7LRR1	Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.	Spindle pole body component.	0.996
NEOLI_001308	NEOLI_003565	A0A1U7LKN5	A0A1U7LTF1	Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.	Spindle pole body component.	0.996
NEOLI_001308	NEOLI_003587	A0A1U7LKN5	A0A1U7LIQ3	Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.	DASH complex subunit ask1.	0.958
NEOLI_001308	NEOLI_003692	A0A1U7LKN5	A0A1U7LIM8	Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.	Spindle pole body component.	0.977
NEOLI_001308	NEOLI_004078	A0A1U7LKN5	A0A1U7LPQ6	Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.	Spindle pole body component.	0.983
NEOLI_001350	NEOLI_001032	A0A1U7LVD4	A0A1U7LGN3	Putative pentatricopeptide repeat-containing protein.	Putative methylcrotonoyl-CoA carboxylase beta chain, mitochondrial.	0.658
NEOLI_001350	NEOLI_001308	A0A1U7LVD4	A0A1U7LKN5	Putative pentatricopeptide repeat-containing protein.	Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.	0.756
NEOLI_001350	NEOLI_001412	A0A1U7LVD4	A0A1U7LHR7	Putative pentatricopeptide repeat-containing protein.	Histone H2B; Belongs to the histone H2B family.	0.641
NEOLI_001350	NEOLI_002396	A0A1U7LVD4	A0A1U7LJN7	Putative pentatricopeptide repeat-containing protein.	Histone H3-like centromeric protein cnp1.	0.717
NEOLI_001350	NEOLI_002832	A0A1U7LVD4	A0A1U7LSU6	Putative pentatricopeptide repeat-containing protein.	Uncharacterized protein.	0.671
NEOLI_001350	NEOLI_003295	A0A1U7LVD4	A0A1U7LRR1	Putative pentatricopeptide repeat-containing protein.	Spindle pole body component.	0.743
NEOLI_001350	NEOLI_003565	A0A1U7LVD4	A0A1U7LTF1	Putative pentatricopeptide repeat-containing protein.	Spindle pole body component.	0.734
NEOLI_001350	NEOLI_003587	A0A1U7LVD4	A0A1U7LIQ3	Putative pentatricopeptide repeat-containing protein.	DASH complex subunit ask1.	0.743
NEOLI_001350	NEOLI_003692	A0A1U7LVD4	A0A1U7LIM8	Putative pentatricopeptide repeat-containing protein.	Spindle pole body component.	0.743
NEOLI_001350	NEOLI_004078	A0A1U7LVD4	A0A1U7LPQ6	Putative pentatricopeptide repeat-containing protein.	Spindle pole body component.	0.739
NEOLI_001412	NEOLI_001350	A0A1U7LHR7	A0A1U7LVD4	Histone H2B; Belongs to the histone H2B family.	Putative pentatricopeptide repeat-containing protein.	0.641
NEOLI_001412	NEOLI_002396	A0A1U7LHR7	A0A1U7LJN7	Histone H2B; Belongs to the histone H2B family.	Histone H3-like centromeric protein cnp1.	0.999
NEOLI_001412	NEOLI_002832	A0A1U7LHR7	A0A1U7LSU6	Histone H2B; Belongs to the histone H2B family.	Uncharacterized protein.	0.928

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

12

PPI enrichment p-value:

< 1.0e-16

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

11 of 89

1.08

1.45

1.48e-09

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

10 of 44

1.34

2.24

1.27e-10

GO:0019843

rRNA binding

7 of 36

1.28

1.58

2.71e-06

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

11 of 48

1.35

2.46

3.41e-13

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:172

Ribonucleoprotein

8 of 15

1.72

3.5

4.23e-11

CL:128

Structural constituent of ribosome

11 of 42

1.41

2.68

2.65e-13

CL:130

Structural constituent of ribosome

10 of 36

1.43

2.67

3.68e-12

CL:174

Mixed, incl. Large ribosomal subunit rRNA binding, and Protein-containing complex assembly

3 of 6

1.69

1.42

0.00084

CL:192

Methylation, and rRNA-binding

2 of 5

1.59

0.8

0.0236

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03010

Ribosome

11 of 48

1.35

2.46

3.61e-13

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005840

Ribosome

9 of 34

1.41

2.36

6.70e-10

GOCC:0043229

Intracellular organelle

10 of 111

0.94

1.08

9.03e-08

GOCC:0005622

Intracellular

11 of 376

0.45

0.39

0.00023

GOCC:0110165

Cellular anatomical entity

11 of 562

0.28

0.25

0.0155

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

11 of 47

1.36

2.48

4.22e-13

KW-0687

Ribonucleoprotein

11 of 47

1.36

2.48

4.22e-13

KW-0699

rRNA-binding

6 of 30

1.29

1.5

1.27e-05

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (20%) [HD]

Permalink

Credits

Access

Info

About

STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.

Network

Fusion

Experiments

Cooccurrence

Databases

Coexpression

Textmining

Neighborhood

© STRING Consortium 2024

Credits

Access

Info

About