node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
TI01_1373 | TI01_2506 | TI01_1373 | TI01_2506 | Transcriptional regulator, MerR family. | DnaJ-class molecular chaperone CbpA. | 0.921 |
TI01_1373 | dnaK | TI01_1373 | TI01_1887 | Transcriptional regulator, MerR family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.525 |
TI01_1373 | grpE | TI01_1373 | TI01_1886 | Transcriptional regulator, MerR family. | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 0.484 |
TI01_2506 | TI01_1373 | TI01_2506 | TI01_1373 | DnaJ-class molecular chaperone CbpA. | Transcriptional regulator, MerR family. | 0.921 |
TI01_2506 | dnaK | TI01_2506 | TI01_1887 | DnaJ-class molecular chaperone CbpA. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.999 |
TI01_2506 | grpE | TI01_2506 | TI01_1886 | DnaJ-class molecular chaperone CbpA. | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 0.945 |
TI01_2506 | htpG | TI01_2506 | TI01_0646 | DnaJ-class molecular chaperone CbpA. | Chaperone protein HtpG; Molecular chaperone. Has ATPase activity. | 0.978 |
TI01_2506 | rplC | TI01_2506 | TI01_2422 | DnaJ-class molecular chaperone CbpA. | LSU ribosomal protein L3p (L3e); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.918 |
TI01_2506 | rplK | TI01_2506 | TI01_2411 | DnaJ-class molecular chaperone CbpA. | LSU ribosomal protein L11p (L12e); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.919 |
TI01_2506 | rplM | TI01_2506 | TI01_0877 | DnaJ-class molecular chaperone CbpA. | LSU ribosomal protein L13p (L13Ae); This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.921 |
TI01_2506 | rplN | TI01_2506 | TI01_2432 | DnaJ-class molecular chaperone CbpA. | LSU ribosomal protein L14p (L23e); Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. | 0.915 |
TI01_2506 | rplO | TI01_2506 | TI01_2441 | DnaJ-class molecular chaperone CbpA. | LSU ribosomal protein L15p (L27Ae); Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.919 |
TI01_2506 | rplQ | TI01_2506 | TI01_2448 | DnaJ-class molecular chaperone CbpA. | LSU ribosomal protein L17p. | 0.928 |
dnaK | TI01_1373 | TI01_1887 | TI01_1373 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Transcriptional regulator, MerR family. | 0.525 |
dnaK | TI01_2506 | TI01_1887 | TI01_2506 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | DnaJ-class molecular chaperone CbpA. | 0.999 |
dnaK | grpE | TI01_1887 | TI01_1886 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 0.999 |
dnaK | htpG | TI01_1887 | TI01_0646 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Chaperone protein HtpG; Molecular chaperone. Has ATPase activity. | 0.999 |
dnaK | rplC | TI01_1887 | TI01_2422 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | LSU ribosomal protein L3p (L3e); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.786 |
dnaK | rplK | TI01_1887 | TI01_2411 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | LSU ribosomal protein L11p (L12e); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.703 |
dnaK | rplM | TI01_1887 | TI01_0877 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | LSU ribosomal protein L13p (L13Ae); This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.779 |