STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EQC47986.1Hsp20/alpha crystallin family protein; Belongs to the small heat shock protein (HSP20) family. (165 aa)    
Predicted Functional Partners:
clpA
ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family.
  
 
 0.748
clpB
Chaperone protein ClpB; Belongs to the ClpA/ClpB family.
  
 
 0.748
M900_1748
Hsp90 protein.
  
 
 0.622
grpE
Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...]
  
  
 0.584
M900_1407
DnaK domain protein.
  
 
 0.583
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.583
EQC48006.1
Transglycosylase.
       0.578
EQC48005.1
FxsA cytoplasmic membrane protein.
   
    0.519
M900_2268
DnaJ domain protein.
  
 
 0.439
EQC47992.1
Hypothetical protein; Identified by glimmer; putative.
       0.427
Your Current Organism:
Bacteriovorax sp. Seq25V
NCBI taxonomy Id: 1201288
Other names: B. sp. Seq25_V, Bacteriovorax sp. Seq25_V
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.