STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dapBDihydrodipicolinate reductase; Belongs to the DapB family. (231 aa)    
Predicted Functional Partners:
dapA
Dihydrodipicolinate synthase; Belongs to the DapA family.
 
 
 0.983
dapD
Tetrahydrodipicolinate N-succinyltransferase.
  
 
 0.941
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
    0.843
A33U_087
Hypothetical protein.
       0.773
pdt
Putative prephenate dehydratase.
     
 0.762
thrA
Homoserine dehydrogenase.
  
  
 0.718
rluD
Ribosomal large subunit pseudouridine synthase.
   
   0.684
grpE
Chaperone protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-d [...]
  
    0.579
lysA
Diaminopimelate decarboxylase.
  
  
 0.546
asd
Aspartate-semialdehyde dehydrogenase; Belongs to the aspartate-semialdehyde dehydrogenase family.
  
  
 0.536
Your Current Organism:
Carsonella ruddii CE Thao2000
NCBI taxonomy Id: 1202536
Other names: C. Carsonella ruddii CE isolate Thao2000, Candidatus Carsonella ruddii CE isolate Thao2000, endosymbiont of Ctenarytaina eucalypti isolate Thao2000
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.