| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| B005_0368 | carA | B005_0368 | B005_0062 | Carbamoyl-phosphate synthase L chain, ATP binding domain protein. | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | 0.991 |
| B005_0368 | carB | B005_0368 | B005_0061 | Carbamoyl-phosphate synthase L chain, ATP binding domain protein. | Carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | 0.900 |
| B005_0368 | purA | B005_0368 | B005_2227 | Carbamoyl-phosphate synthase L chain, ATP binding domain protein. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.418 |
| B005_0368 | pyrB | B005_0368 | B005_0064 | Carbamoyl-phosphate synthase L chain, ATP binding domain protein. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.972 |
| B005_0368 | pyrC | B005_0368 | B005_0063 | Carbamoyl-phosphate synthase L chain, ATP binding domain protein. | Dihydroorotase, multifunctional complex type domain protein; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.596 |
| B005_0368 | pyrE | B005_0368 | B005_2231 | Carbamoyl-phosphate synthase L chain, ATP binding domain protein. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.750 |
| B005_0368 | pyrR | B005_0368 | B005_0065 | Carbamoyl-phosphate synthase L chain, ATP binding domain protein. | Bifunctional pyrR domain protein; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. | 0.727 |
| B005_3666 | purA | B005_3666 | B005_2227 | Asparagine synthase family protein. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.915 |
| B005_3666 | pyrB | B005_3666 | B005_0064 | Asparagine synthase family protein. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.917 |
| B005_5104 | pyrB | B005_5104 | B005_0064 | Amidohydrolase family protein. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.911 |
| B005_5104 | pyrC | B005_5104 | B005_0063 | Amidohydrolase family protein. | Dihydroorotase, multifunctional complex type domain protein; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.900 |
| carA | B005_0368 | B005_0062 | B005_0368 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Carbamoyl-phosphate synthase L chain, ATP binding domain protein. | 0.991 |
| carA | carB | B005_0062 | B005_0061 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | 0.999 |
| carA | purA | B005_0062 | B005_2227 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.607 |
| carA | pyrB | B005_0062 | B005_0064 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
| carA | pyrC | B005_0062 | B005_0063 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Dihydroorotase, multifunctional complex type domain protein; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.995 |
| carA | pyrE | B005_0062 | B005_2231 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.846 |
| carA | pyrR | B005_0062 | B005_0065 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Bifunctional pyrR domain protein; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. | 0.847 |
| carB | B005_0368 | B005_0061 | B005_0368 | Carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | Carbamoyl-phosphate synthase L chain, ATP binding domain protein. | 0.900 |
| carB | carA | B005_0061 | B005_0062 | Carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | 0.999 |