STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
B005_0831formamidopyrimidine-DNA glycosylase H2TH domain protein; Belongs to the FPG family. (292 aa)    
Predicted Functional Partners:
polA
DNA polymerase I family protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.913
B005_3559
DEAD/DEAH box helicase family protein.
  
  
 0.725
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
   
  
 0.717
B005_0103
Exonuclease, DNA polymerase III, epsilon subunit family domain protein.
  
  
 0.630
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
  
  
 0.612
B005_3486
DNA polymerase A family protein.
 
  
 0.590
B005_0832
Superfamily I DNA and RNA helicase and helicase subunit.
       0.559
B005_0830
Periplasmic binding s and sugar binding domain of LacI family protein.
       0.486
B005_4294
HAD hydrolase, IA, variant 1 family protein.
  
   
 0.484
B005_4685
Exonuclease family protein.
   
  
 0.484
Your Current Organism:
Nocardiopsis alba
NCBI taxonomy Id: 1205910
Other names: N. alba ATCC BAA-2165, Nocardiopsis alba ATCC BAA-2165, Nocardiopsis alba BE74
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.