| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| B005_1497 | B005_3813 | B005_1497 | B005_3813 | RNA 2'-O ribose methyltransferase substrate binding family protein; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | Pseudouridine synthase, RluA family protein; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.690 |
| B005_1497 | cgtA | B005_1497 | B005_0482 | RNA 2'-O ribose methyltransferase substrate binding family protein; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | Obg family GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.552 |
| B005_1497 | cysS | B005_1497 | B005_1498 | RNA 2'-O ribose methyltransferase substrate binding family protein; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | cysteine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.717 |
| B005_1497 | era | B005_1497 | B005_3616 | RNA 2'-O ribose methyltransferase substrate binding family protein; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.640 |
| B005_1497 | ffh | B005_1497 | B005_3075 | RNA 2'-O ribose methyltransferase substrate binding family protein; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.592 |
| B005_1497 | ftsY | B005_1497 | B005_3071 | RNA 2'-O ribose methyltransferase substrate binding family protein; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.568 |
| B005_1497 | pheT | B005_1497 | B005_0027 | RNA 2'-O ribose methyltransferase substrate binding family protein; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | phenylalanine--tRNA ligase, beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.731 |
| B005_1497 | rplC | B005_1497 | B005_2704 | RNA 2'-O ribose methyltransferase substrate binding family protein; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.597 |
| B005_1497 | rplK | B005_1497 | B005_2681 | RNA 2'-O ribose methyltransferase substrate binding family protein; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.747 |
| B005_1497 | rplM | B005_1497 | B005_2738 | RNA 2'-O ribose methyltransferase substrate binding family protein; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.615 |
| B005_3813 | B005_1497 | B005_3813 | B005_1497 | Pseudouridine synthase, RluA family protein; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | RNA 2'-O ribose methyltransferase substrate binding family protein; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 0.690 |
| B005_3813 | cgtA | B005_3813 | B005_0482 | Pseudouridine synthase, RluA family protein; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | Obg family GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.814 |
| B005_3813 | pheT | B005_3813 | B005_0027 | Pseudouridine synthase, RluA family protein; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | phenylalanine--tRNA ligase, beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.650 |
| B005_3813 | rplC | B005_3813 | B005_2704 | Pseudouridine synthase, RluA family protein; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.879 |
| B005_3813 | rplK | B005_3813 | B005_2681 | Pseudouridine synthase, RluA family protein; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.845 |
| B005_3813 | rplM | B005_3813 | B005_2738 | Pseudouridine synthase, RluA family protein; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.865 |
| cgtA | B005_1497 | B005_0482 | B005_1497 | Obg family GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | RNA 2'-O ribose methyltransferase substrate binding family protein; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 0.552 |
| cgtA | B005_3813 | B005_0482 | B005_3813 | Obg family GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Pseudouridine synthase, RluA family protein; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.814 |
| cgtA | era | B005_0482 | B005_3616 | Obg family GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.555 |
| cgtA | ffh | B005_0482 | B005_3075 | Obg family GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.478 |