STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sucCsuccinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (393 aa)    
Predicted Functional Partners:
sucD
succinate-CoA ligase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 0.999
B005_1097
4Fe-4S binding domain protein.
 
 0.985
sucA
Oxoglutarate dehydrogenase (succinyl-transferring), E1 component.
 
 
 0.981
B005_2653
Acceptor oxidoreductase, alpha subunit.
  
 
 0.978
B005_0131
2-oxoacid dehydrogenases acyltransferase family protein.
 
 0.972
sdhA
Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.
  
 0.972
gltA
Citrate (Si)-synthase; Belongs to the citrate synthase family.
 
 
 0.970
B005_0130
Glycine cleavage H-family protein.
  
 0.968
B005_2846
methylmalonyl-CoA mutase C-terminal domain protein.
  
 
 0.948
B005_2652
Thiamine pyrophosphate enzyme, C-terminal TPP binding domain protein.
  
 
 0.933
Your Current Organism:
Nocardiopsis alba
NCBI taxonomy Id: 1205910
Other names: N. alba ATCC BAA-2165, Nocardiopsis alba ATCC BAA-2165, Nocardiopsis alba BE74
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.