STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (320 aa)    
Predicted Functional Partners:
hom
Homoserine dehydrogenase.
 
 0.997
B005_3192
Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
 
 
 0.994
B005_1379
Threonine synthase.
 
 
 0.975
purM
Phosphoribosylformylglycinamidine cyclo-ligase.
 
    
 0.907
metH
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.896
B005_3718
Cobalamin-independent synthase, Catalytic domain protein; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
   
 
 0.854
B005_3295
L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family.
  
 
 0.846
B005_3972
O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase family protein.
 
  
 0.838
metB
Cystathionine gamma-synthase MetB.
  
 
 0.836
B005_0231
Aminotransferase class IV family protein.
  
 
 0.834
Your Current Organism:
Nocardiopsis alba
NCBI taxonomy Id: 1205910
Other names: N. alba ATCC BAA-2165, Nocardiopsis alba ATCC BAA-2165, Nocardiopsis alba BE74
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