SHG28634.1 protein (Jatrophihabitans endophyticus)

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second shell of interactors

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Edges:

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

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Score

SHG28634.1

Pyruvyltransferase. (264 aa)

Predicted Functional Partners:

SHG28594.1

0.711

SHG28740.1

0.686

SHG28667.1

0.593

SHG28708.1

0.499

SHG28782.1

0.499

SHF57156.1

0.464

SHG52011.1

0.461

SHG28813.1

0.421

SHF65153.1

0.415

Your Current Organism:

Jatrophihabitans endophyticus

NCBI taxonomy Id: 1206085
Other names: DSM 45627, Frankia sp. S9-650, J. endophyticus, Jatrophihabitans endophyticus Madhaiyan et al. 2013, KACC 16232, strain S9-650

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SHF57156.1	SHF65153.1	SAMN05443575_0323	SAMN05443575_0546	Amino acid adenylation domain-containing protein.	Undecaprenyl-diphosphatase.	0.956
SHF57156.1	SHG28594.1	SAMN05443575_0323	SAMN05443575_1919	Amino acid adenylation domain-containing protein.	Membrane protein involved in the export of O-antigen and teichoic acid; Non-canonical start codon; manually curated.	0.457
SHF57156.1	SHG28634.1	SAMN05443575_0323	SAMN05443575_1920	Amino acid adenylation domain-containing protein.	Pyruvyltransferase.	0.464
SHF57156.1	SHG28667.1	SAMN05443575_0323	SAMN05443575_1921	Amino acid adenylation domain-containing protein.	Hypothetical protein.	0.697
SHF57156.1	SHG28708.1	SAMN05443575_0323	SAMN05443575_1922	Amino acid adenylation domain-containing protein.	Glycosyltransferase involved in cell wall bisynthesis.	0.549
SHF57156.1	SHG28782.1	SAMN05443575_0323	SAMN05443575_1924	Amino acid adenylation domain-containing protein.	Glycosyltransferase involved in cell wall bisynthesis.	0.549
SHF57156.1	SHG52011.1	SAMN05443575_0323	SAMN05443575_2152	Amino acid adenylation domain-containing protein.	Ferredoxin-NADP reductase.	0.942
SHF65153.1	SHF57156.1	SAMN05443575_0546	SAMN05443575_0323	Undecaprenyl-diphosphatase.	Amino acid adenylation domain-containing protein.	0.956
SHF65153.1	SHG28634.1	SAMN05443575_0546	SAMN05443575_1920	Undecaprenyl-diphosphatase.	Pyruvyltransferase.	0.415
SHF65153.1	SHG28708.1	SAMN05443575_0546	SAMN05443575_1922	Undecaprenyl-diphosphatase.	Glycosyltransferase involved in cell wall bisynthesis.	0.426
SHF65153.1	SHG28782.1	SAMN05443575_0546	SAMN05443575_1924	Undecaprenyl-diphosphatase.	Glycosyltransferase involved in cell wall bisynthesis.	0.426
SHG28594.1	SHF57156.1	SAMN05443575_1919	SAMN05443575_0323	Membrane protein involved in the export of O-antigen and teichoic acid; Non-canonical start codon; manually curated.	Amino acid adenylation domain-containing protein.	0.457
SHG28594.1	SHG28634.1	SAMN05443575_1919	SAMN05443575_1920	Membrane protein involved in the export of O-antigen and teichoic acid; Non-canonical start codon; manually curated.	Pyruvyltransferase.	0.711
SHG28594.1	SHG28708.1	SAMN05443575_1919	SAMN05443575_1922	Membrane protein involved in the export of O-antigen and teichoic acid; Non-canonical start codon; manually curated.	Glycosyltransferase involved in cell wall bisynthesis.	0.523
SHG28594.1	SHG28740.1	SAMN05443575_1919	SAMN05443575_1923	Membrane protein involved in the export of O-antigen and teichoic acid; Non-canonical start codon; manually curated.	Beta-1,4-mannosyltransferase&#160.	0.517
SHG28594.1	SHG28782.1	SAMN05443575_1919	SAMN05443575_1924	Membrane protein involved in the export of O-antigen and teichoic acid; Non-canonical start codon; manually curated.	Glycosyltransferase involved in cell wall bisynthesis.	0.546
SHG28634.1	SHF57156.1	SAMN05443575_1920	SAMN05443575_0323	Pyruvyltransferase.	Amino acid adenylation domain-containing protein.	0.464
SHG28634.1	SHF65153.1	SAMN05443575_1920	SAMN05443575_0546	Pyruvyltransferase.	Undecaprenyl-diphosphatase.	0.415
SHG28634.1	SHG28594.1	SAMN05443575_1920	SAMN05443575_1919	Pyruvyltransferase.	Membrane protein involved in the export of O-antigen and teichoic acid; Non-canonical start codon; manually curated.	0.711
SHG28634.1	SHG28667.1	SAMN05443575_1920	SAMN05443575_1921	Pyruvyltransferase.	Hypothetical protein.	0.593

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Network Stats

number of nodes:

11

number of edges:

17

average node degree:

3.09

avg. local clustering coefficient:

0.787

expected number of edges:

10

PPI enrichment p-value:

0.0391

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0055085

Transmembrane transport

10 of 249

0.85

0.84

1.28e-05

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0042626

ATPase-coupled transmembrane transporter activity

5 of 57

1.19

1.12

0.00033

GO:0140359

ABC-type transporter activity

4 of 39

1.26

1.04

0.0016

GO:0005524

ATP binding

10 of 261

0.83

0.82

1.05e-05

GO:0022857

Transmembrane transporter activity

8 of 210

0.83

0.76

9.66e-05

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016020

Membrane

10 of 571

0.49

0.38

0.0041

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2923

Transcription regulators MarR/SlyA-like, and ABC transporter transmembrane region

4 of 5

2.15

2.51

9.61e-06

CL:2919

Mixed, incl. ABC transporter transmembrane region, and ABC transporter, CbiO/EcfA subunit

5 of 31

1.46

1.59

5.78e-05

CL:2914

Mixed, incl. ABC transporters, and Latent infection - Other responses of Mtb to phagocytosis

9 of 108

1.17

1.51

1.53e-07

CL:2915

Mixed, incl. ABC transporters, and Latent infection - Other responses of Mtb to phagocytosis

8 of 93

1.18

1.45

1.18e-06

CL:2916

Mixed, incl. Latent infection - Other responses of Mtb to phagocytosis, and ABC transporters

7 of 82

1.18

1.34

9.66e-06

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

adc02010

ABC transporters

6 of 90

1.07

0.97

0.00042

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-1222449

Mtb iron assimilation by chelation

2 of 15

1.37

0.62

0.0483

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005886

Plasma membrane

7 of 236

0.72

0.49

0.0111

GOCC:0016020

Membrane

8 of 319

0.65

0.45

0.0111

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-1278

Translocase

3 of 10

1.73

1.29

0.0020

KW-0067

ATP-binding

10 of 211

0.92

1.02

4.39e-07

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR017871

ABC transporter-like, conserved site

10 of 60

1.47

2.74

1.49e-11

IPR003439

ABC transporter-like, ATP-binding domain

10 of 67

1.42

2.57

2.05e-11

IPR003593

AAA+ ATPase domain

10 of 84

1.32

2.18

1.12e-10

IPR027417

P-loop containing nucleoside triphosphate hydrolase

10 of 157

1.05

1.32

3.16e-08

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00382

ATPases associated with a variety of cellular activities

10 of 81

1.34

2.29

2.19e-11

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