STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHH31256.1Type IV secretory system Conjugative DNA transfer. (712 aa)    
Predicted Functional Partners:
SHH31178.1
DNA modification methylase; Belongs to the N(4)/N(6)-methyltransferase family.
 
     0.898
SHH31222.1
Replication-relaxation.
       0.835
SHF50386.1
HNH endonuclease.
 
 
 
 0.688
SHH53578.1
HNH endonuclease.
 
 
 
 0.677
SHH31019.1
Site-specific DNA recombinase; Manually curated.
 
    0.662
SHG82262.1
Hypothetical protein.
   
 
 0.604
SHH02842.1
5-methylcytosine-specific restriction endonuclease McrA.
   
 
 0.604
SHH64403.1
HNH endonuclease.
   
 
 0.604
SHH31144.1
Hypothetical protein.
       0.592
topA
DNA topoisomerase-1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.527
Your Current Organism:
Jatrophihabitans endophyticus
NCBI taxonomy Id: 1206085
Other names: DSM 45627, Frankia sp. S9-650, J. endophyticus, Jatrophihabitans endophyticus Madhaiyan et al. 2013, KACC 16232, strain S9-650
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