STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BN7_5303tRNA-splicing endonuclease subunit Sen34; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structura [...] (292 aa)    
Predicted Functional Partners:
BN7_6345
tRNA-splicing endonuclease subunit Sen2; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural [...]
    
 0.967
BN7_2835
Putative tRNA-splicing endonuclease subunit.
  
 0.892
BN7_4433
tRNA-splicing endonuclease subunit.
    
 0.787
CLP1
mRNA cleavage and polyadenylation factor CLP1; Required for endonucleolytic cleavage during polyadenylation- dependent pre-mRNA 3'-end formation.
    
 0.735
BN7_2570b
Zinc phosphodiesterase.
  
  
 0.560
RPC5
DNA-directed RNA polymerase III subunit.
   
    0.514
BN7_1603
tRNA ligase.
      
 0.507
BN7_4172
Homoserine dehydrogenase.
      
 0.506
SYR1
Arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
      
 0.485
BN7_2264
Putative RNA 2'-phosphotransferase.
      
 0.483
Your Current Organism:
Wickerhamomyces ciferrii
NCBI taxonomy Id: 1206466
Other names: W. ciferrii NRRL Y-1031, Wickerhamomyces ciferrii NRRL Y-1031
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