STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDSE_02797,8-dihydro-8-oxoguanine triphosphatase; Coenzyme metabolism; SecretomeP prediction: 0.07; Protein involved in hydrolase activity; Belongs to the Nudix hydrolase family. (322 aa)    
Predicted Functional Partners:
CDSE_0275
Phosphomethylpyrimidine kinase; Coenzyme metabolism; SecretomeP prediction: 0.08; Protein involved in transferase activity.
 
  
 0.848
CDSE_0280
AAA+ superfamily ATPase; General function prediction only; SecretomeP prediction: 0.1; Protein involved in nucleoside-triphosphatase activity.
  
    0.841
argJ
Glutamate N-acetyltransferase/amino-acid N-acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
  
  
 0.822
thiG
Thiamine biosynthesis ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
  
 0.763
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
   
 0.750
CDSE_0047
Exoribonuclease II; Transcription; SecretomeP prediction: 0.24; Protein involved in ribonuclease activity and hydrolase activity.
  
  0.733
rnr
Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
  
  0.733
CDSE_0112
Superfamily II DNA and RNA helicase; DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis; SecretomeP prediction: 0.73; Protein involved in hydrolase activity; Belongs to the DEAD box helicase family.
    
 0.721
CDSE_0833
ATP-dependent RNA helicase RhlE; DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis; SecretomeP prediction: 0.14; Protein involved in hydrolase activity; Belongs to the DEAD box helicase family.
    
 0.721
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
   
 
 0.719
Your Current Organism:
Kinetoplastibacterium desouzaii
NCBI taxonomy Id: 1208919
Other names: C. Kinetoplastibacterium desouzaii TCC079E, Candidatus Kinetoplastibacterium desouzaii TCC079E
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.