node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDF86758.1 | SDF87590.1 | SAMN05421791_101290 | SAMN05421791_101311 | Exonuclease, DNA polymerase III, epsilon subunit family. | DNA polymerase-3 subunit alpha. | 0.937 |
SDF86758.1 | SDF89438.1 | SAMN05421791_101290 | SAMN05421791_101363 | Exonuclease, DNA polymerase III, epsilon subunit family. | DNA polymerase III, delta subunit. | 0.936 |
SDF86758.1 | SDG24254.1 | SAMN05421791_101290 | SAMN05421791_10481 | Exonuclease, DNA polymerase III, epsilon subunit family. | DNA polymerase-3 subunit delta'. | 0.902 |
SDF86758.1 | SDG27711.1 | SAMN05421791_101290 | SAMN05421791_104200 | Exonuclease, DNA polymerase III, epsilon subunit family. | DNA polymerase-3 subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | 0.952 |
SDF86758.1 | dnaX | SAMN05421791_101290 | SAMN05421791_10486 | Exonuclease, DNA polymerase III, epsilon subunit family. | DNA polymerase-3 subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.902 |
SDF86758.1 | ligA | SAMN05421791_101290 | SAMN05421791_10611 | Exonuclease, DNA polymerase III, epsilon subunit family. | DNA ligase (NAD+); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. | 0.627 |
SDF86758.1 | mutL | SAMN05421791_101290 | SAMN05421791_101316 | Exonuclease, DNA polymerase III, epsilon subunit family. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.912 |
SDF86758.1 | polC | SAMN05421791_101290 | SAMN05421791_101110 | Exonuclease, DNA polymerase III, epsilon subunit family. | DNA polymerase-3 subunit alpha; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.592 |
SDF86758.1 | uvrC | SAMN05421791_101290 | SAMN05421791_10617 | Exonuclease, DNA polymerase III, epsilon subunit family. | Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.723 |
SDF87590.1 | SDF86758.1 | SAMN05421791_101311 | SAMN05421791_101290 | DNA polymerase-3 subunit alpha. | Exonuclease, DNA polymerase III, epsilon subunit family. | 0.937 |
SDF87590.1 | SDF89438.1 | SAMN05421791_101311 | SAMN05421791_101363 | DNA polymerase-3 subunit alpha. | DNA polymerase III, delta subunit. | 0.999 |
SDF87590.1 | SDG24254.1 | SAMN05421791_101311 | SAMN05421791_10481 | DNA polymerase-3 subunit alpha. | DNA polymerase-3 subunit delta'. | 0.993 |
SDF87590.1 | SDG27711.1 | SAMN05421791_101311 | SAMN05421791_104200 | DNA polymerase-3 subunit alpha. | DNA polymerase-3 subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | 0.999 |
SDF87590.1 | dnaX | SAMN05421791_101311 | SAMN05421791_10486 | DNA polymerase-3 subunit alpha. | DNA polymerase-3 subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.994 |
SDF87590.1 | ligA | SAMN05421791_101311 | SAMN05421791_10611 | DNA polymerase-3 subunit alpha. | DNA ligase (NAD+); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. | 0.765 |
SDF87590.1 | mutL | SAMN05421791_101311 | SAMN05421791_101316 | DNA polymerase-3 subunit alpha. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.720 |
SDF87590.1 | polC | SAMN05421791_101311 | SAMN05421791_101110 | DNA polymerase-3 subunit alpha. | DNA polymerase-3 subunit alpha; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.938 |
SDF87590.1 | uvrC | SAMN05421791_101311 | SAMN05421791_10617 | DNA polymerase-3 subunit alpha. | Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.684 |
SDF89404.1 | SDF89438.1 | SAMN05421791_101362 | SAMN05421791_101363 | Diaminopimelate dehydrogenase; Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate. | DNA polymerase III, delta subunit. | 0.732 |
SDF89438.1 | SDF86758.1 | SAMN05421791_101363 | SAMN05421791_101290 | DNA polymerase III, delta subunit. | Exonuclease, DNA polymerase III, epsilon subunit family. | 0.936 |