STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDG27449.1c-di-AMP phosphodiesterase, consists of a GGDEF-like and DHH domains; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. (665 aa)    
Predicted Functional Partners:
rplI
Large subunit ribosomal protein L9; Binds to the 23S rRNA.
 
    0.980
SDG27400.1
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
  
  
 0.761
tmcAL
Predicted nucleotidyltransferase; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac- AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
  
     0.682
rpsR
Small subunit ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.
       0.560
polC
DNA polymerase-3 subunit alpha; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
  
     0.542
SDG27371.1
Hypothetical protein.
       0.530
SDG27508.1
Single-strand DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
       0.525
rpsF
Small subunit ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
       0.468
SDG27344.1
acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
       0.461
SDG24282.1
Uncharacterized protein YaaQ.
  
  
 0.447
Your Current Organism:
Facklamia miroungae
NCBI taxonomy Id: 120956
Other names: CCUG 42728, CIP 106764, F. miroungae, Facklamia miroungae Hoyles et al. 2001, Facklamia sp. CCUG 42728, Facklamia sp. CCUG42728, strain A/G13/99/2
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