STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDG42222.1Alkylmercury lyase. (187 aa)    
Predicted Functional Partners:
SDG42182.1
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase).
  
 0.925
SDG42158.1
Pyruvate dehydrogenase E1 component beta subunit.
  
 0.912
SDG31586.1
Pyruvate dehydrogenase E1 component beta subunit.
  
 0.865
SDG13865.1
Dihydrolipoamide dehydrogenase/pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase)/2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase).
  
 0.859
SDG31612.1
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase).
  
 0.859
SDG00174.1
Thiol-disulfide isomerase or thioredoxin.
  
 0.841
pdhA-2
Pyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
  
 
 0.764
SDG32895.1
Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide.
  
 
 0.720
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
   
 0.702
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.665
Your Current Organism:
Facklamia miroungae
NCBI taxonomy Id: 120956
Other names: CCUG 42728, CIP 106764, F. miroungae, Facklamia miroungae Hoyles et al. 2001, Facklamia sp. CCUG 42728, Facklamia sp. CCUG42728, strain A/G13/99/2
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