STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
E0VEK1_PEDHCUncharacterized protein. (1764 aa)    
Predicted Functional Partners:
E0VAJ6_PEDHC
Charged multivesicular body protein 4C, putative.
    
 0.994
E0W250_PEDHC
Signal transducing adapter molecule, putative.
   
 0.921
E0VST4_PEDHC
Protein E, putative.
   
 0.887
E0W0X3_PEDHC
Magnesium-dependent phosphatase, putative.
    
 0.854
E0VNV3_PEDHC
Uncharacterized protein.
    
 0.842
E0W212_PEDHC
Receptor protein-tyrosine kinase.
    
 0.756
E0VZP3_PEDHC
Uncharacterized protein.
    
 0.736
E0V9Y3_PEDHC
Leucyl-tRNA synthetase, putative; Belongs to the class-I aminoacyl-tRNA synthetase family.
   
  
 0.696
E0VTB6_PEDHC
Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.
   
 0.679
E0VRD1_PEDHC
Zinc finger protein FYVE domain-containing protein, putative.
   
 
 0.673
Your Current Organism:
Pediculus humanus
NCBI taxonomy Id: 121224
Other names: P. humanus corporis, Pediculus humanus corporis, Pediculus humanus humanus, human body lice, human body louse
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