STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
E0VF80_PEDHCDNA polymerase theta, putative. (1350 aa)    
Predicted Functional Partners:
E0VRP4_PEDHC
Exonuclease, putative.
  
 
 0.723
E0VP82_PEDHC
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
  
 
 0.722
E0VKU4_PEDHC
Uncharacterized protein.
   
 0.658
E0VFW2_PEDHC
Double-strand break repair protein MRE11A, putative; Belongs to the MRE11/RAD32 family.
   
 0.626
E0VVF4_PEDHC
DNA excision repair protein, putative.
  
 
 0.605
E0VL49_PEDHC
EIP28, putative.
   
  
 0.581
E0W0B2_PEDHC
DNA repair protein RAD50, putative.
  
 
 0.577
E0VXB6_PEDHC
Poly [ADP-ribose] polymerase.
     
 0.561
E0VA47_PEDHC
DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family.
  
  
 0.552
E0VEV6_PEDHC
Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.
   
 
 0.541
Your Current Organism:
Pediculus humanus
NCBI taxonomy Id: 121224
Other names: P. humanus corporis, Pediculus humanus corporis, Pediculus humanus humanus, human body lice, human body louse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.