STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
E0VGS7_PEDHCFolate gamma-glutamyl hydrolase. (320 aa)    
Predicted Functional Partners:
E0VWM2_PEDHC
Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.
     
 0.912
E0W1C2_PEDHC
Dihydrofolate reductase, putative; Belongs to the dihydrofolate reductase family.
     
 0.903
E0VXP6_PEDHC
Uncharacterized protein; Belongs to the SKP1 family.
   
 0.767
E0VCH5_PEDHC
RING-box protein 1A, putative.
    
 0.602
E0VJW9_PEDHC
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.
    
   0.582
E0VHF5_PEDHC
CULLIN_2 domain-containing protein; Belongs to the cullin family.
    
 0.533
E0W079_PEDHC
Cullin-1, putative; Belongs to the cullin family.
    
 0.533
E0W291_PEDHC
Cullin-3, putative; Belongs to the cullin family.
    
 0.533
E0VU21_PEDHC
NEDD8 precursor, putative.
    
 0.445
E0VWQ1_PEDHC
Deoxyribodipyrimidine photo-lyase, putative.
    
 0.422
Your Current Organism:
Pediculus humanus
NCBI taxonomy Id: 121224
Other names: P. humanus corporis, Pediculus humanus corporis, Pediculus humanus humanus, human body lice, human body louse
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