STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
E0VHX5_PEDHCE3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1786 aa)    
Predicted Functional Partners:
E0W2X7_PEDHC
Ubiquitin-conjugating enzyme E2-17 kDa, putative; Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.948
E0VZ82_PEDHC
Ubiquitin, putative.
   
 0.829
E0VC00_PEDHC
Ubiquitin protein ligase E3a, putative.
   
 0.796
E0VAM3_PEDHC
Uncharacterized protein.
   
 0.768
E0VYX2_PEDHC
Ssm4 protein, putative.
    
 
 0.728
E0V904_PEDHC
Arginyl-tRNA--protein transferase 1; Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway. Belongs to the R-transferase family.
   
 
 0.713
E0VWF1_PEDHC
RING-CH-type domain-containing protein.
   
 0.651
E0VVC4_PEDHC
HECT, UBA and WWE domain-containing protein, putative.
   
 
 0.641
E0VLM7_PEDHC
Protein purity of essence, putative.
   
  
 0.603
E0VCZ0_PEDHC
E3 ubiquitin protein ligase.
      
 0.587
Your Current Organism:
Pediculus humanus
NCBI taxonomy Id: 121224
Other names: P. humanus corporis, Pediculus humanus corporis, Pediculus humanus humanus, human body lice, human body louse
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