STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
E0VQ67_PEDHCProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)    
Predicted Functional Partners:
E0VP82_PEDHC
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
  
 0.999
E0W2F5_PEDHC
Replication factor C subunit, putative.
  
 0.999
E0VJ22_PEDHC
Replication factor C subunit, putative.
  
 0.998
E0VJY4_PEDHC
Replication factor C subunit, putative.
  
 0.998
E0VJY5_PEDHC
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
   
 0.998
E0W111_PEDHC
DNA polymerase delta small subunit, putative.
   
 0.998
E0VRA4_PEDHC
DNA polymerase IV, putative.
   
 0.997
E0VUR3_PEDHC
DNA polymerase.
  
 0.997
E0VW40_PEDHC
Replication factor C subunit, putative.
  
 0.997
E0VKP6_PEDHC
Replication factor C subunit 1.
   
 0.996
Your Current Organism:
Pediculus humanus
NCBI taxonomy Id: 121224
Other names: P. humanus corporis, Pediculus humanus corporis, Pediculus humanus humanus, human body lice, human body louse
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.