STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
E0W245_PEDHCImportin subunit alpha; Belongs to the importin alpha family. (490 aa)    
Predicted Functional Partners:
E0VS40_PEDHC
Importin beta, putative.
   
 0.879
E0VII7_PEDHC
Exportin-2, putative.
   
 
 0.788
E0VCR9_PEDHC
GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.
   
 
 0.730
E0VJH5_PEDHC
Nuclear cap-binding protein subunit, putative.
   
 
 0.723
E0VY49_PEDHC
Serine/threonine-protein kinase Nek8, putative.
   
 
 0.723
E0W243_PEDHC
Tyrosine--tRNA ligase.
   
  
 0.722
E0VZL3_PEDHC
Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi). The CBC complex is involved in miRNA-mediated RNA interference and is required for primary microRNAs (miRNAs) processing. Also involved in innate immunity via the short interfering RNAs (siRNAs) processing machinery by restricting the viral RNA production. In the CBC complex, Cbp20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requ [...]
    
 
 0.708
E0VXG5_PEDHC
Nuclear pore complex protein nup153, putative.
    
 
 0.706
E0VRW8_PEDHC
X-linked retinitis pigmentosa GTPase regulator, putative.
   
 
 0.703
E0VJL3_PEDHC
HRDC domain-containing protein.
    
   0.678
Your Current Organism:
Pediculus humanus
NCBI taxonomy Id: 121224
Other names: P. humanus corporis, Pediculus humanus corporis, Pediculus humanus humanus, human body lice, human body louse
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