STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFO51970.1COG0776 Bacterial nucleoid DNA-binding protein; Belongs to the bacterial histone-like protein family. (101 aa)    
Predicted Functional Partners:
AFO51969.1
COG0776 Bacterial nucleoid DNA-binding protein; Belongs to the bacterial histone-like protein family.
      
0.802
AFO51968.1
GTP-binding protein Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
   
   0.747
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.613
AFO51967.1
COG0510 Predicted choline kinase involved in LPS biosynthesis.
       0.594
AFO51721.1
COG0258 5'-3' exonuclease (including N-terminal domain of PolI).
   
 
 0.592
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.552
AFO51971.1
Hypothetical protein.
       0.522
AFO51966.1
H+transporting two-sector ATPase delta/subunit epsilon.
       0.521
tuf
Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
  
 
 0.514
AFO52053.1
Inosine-5'-monophosphate dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
   
 
 0.506
Your Current Organism:
Mycoplasma haemolamae
NCBI taxonomy Id: 1212765
Other names: C. Mycoplasma haemolamae str. Purdue, Candidatus Mycoplasma haemolamae str. Purdue, Candidatus Mycoplasma haemolamae strain Purdue
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