STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APY04_0091CRISPR-associated helicase Cas3, protein. (289 aa)    
Predicted Functional Partners:
APY04_0092
CRISPR-associated helicase Cas3, protein.
     0.992
APY04_0051
CRISPR-associated protein, Cas5e family.
 
 
 0.972
APY04_0052
CRISPR-associated protein, Cse4 family.
 
 
 0.972
APY04_0054
CRISPR-associated protein, Cse1 family.
 
 
 0.971
APY04_0048
CRISPR-associated protein, Cas2.
 
  
 0.798
cas1
CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
  
 0.798
APY04_0050
CRISPR-associated protein, Cse3 family.
 
   
 0.794
APY04_0090
Hypothetical protein.
       0.470
Your Current Organism:
Hyphomicrobium sulfonivorans
NCBI taxonomy Id: 121290
Other names: ATCC BAA-113, DSM 13863, H. sulfonivorans, Hyphomicrobium sp. S1, Hyphomicrobium sulfonivorans Borodina et al. 2002, strain S1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.