node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APY04_0471 | APY04_2090 | APY04_0471 | APY04_2090 | Riboflavin kinase; FMN adenylyltransferase; Belongs to the ribF family. | Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.539 |
APY04_0471 | coaD | APY04_0471 | APY04_0403 | Riboflavin kinase; FMN adenylyltransferase; Belongs to the ribF family. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.676 |
APY04_0471 | coaE | APY04_0471 | APY04_2562 | Riboflavin kinase; FMN adenylyltransferase; Belongs to the ribF family. | Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.428 |
APY04_0471 | guaA | APY04_0471 | APY04_1364 | Riboflavin kinase; FMN adenylyltransferase; Belongs to the ribF family. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.426 |
APY04_0471 | guaB | APY04_0471 | APY04_0384 | Riboflavin kinase; FMN adenylyltransferase; Belongs to the ribF family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.596 |
APY04_0471 | nadE-2 | APY04_0471 | APY04_3142 | Riboflavin kinase; FMN adenylyltransferase; Belongs to the ribF family. | NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.430 |
APY04_0552 | APY04_2090 | APY04_0552 | APY04_2090 | Riboflavin kinase; FMN adenylyltransferase; Belongs to the ribF family. | Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.584 |
APY04_0552 | coaD | APY04_0552 | APY04_0403 | Riboflavin kinase; FMN adenylyltransferase; Belongs to the ribF family. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.627 |
APY04_0552 | guaB | APY04_0552 | APY04_0384 | Riboflavin kinase; FMN adenylyltransferase; Belongs to the ribF family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.584 |
APY04_0552 | nadE-2 | APY04_0552 | APY04_3142 | Riboflavin kinase; FMN adenylyltransferase; Belongs to the ribF family. | NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.430 |
APY04_1404 | coaD | APY04_1404 | APY04_0403 | 16S rRNA (guanine(966)-N(2))-methyltransferase, SSU rRNA m(2)G966. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.797 |
APY04_2090 | APY04_0471 | APY04_2090 | APY04_0471 | Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Riboflavin kinase; FMN adenylyltransferase; Belongs to the ribF family. | 0.539 |
APY04_2090 | APY04_0552 | APY04_2090 | APY04_0552 | Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Riboflavin kinase; FMN adenylyltransferase; Belongs to the ribF family. | 0.584 |
APY04_2090 | coaA | APY04_2090 | APY04_2542 | Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantothenate kinase. | 0.897 |
APY04_2090 | coaD | APY04_2090 | APY04_0403 | Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.853 |
APY04_2090 | coaE | APY04_2090 | APY04_2562 | Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.690 |
coaA | APY04_2090 | APY04_2542 | APY04_2090 | Pantothenate kinase. | Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.897 |
coaA | coaD | APY04_2542 | APY04_0403 | Pantothenate kinase. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.850 |
coaD | APY04_0471 | APY04_0403 | APY04_0471 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Riboflavin kinase; FMN adenylyltransferase; Belongs to the ribF family. | 0.676 |
coaD | APY04_0552 | APY04_0403 | APY04_0552 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Riboflavin kinase; FMN adenylyltransferase; Belongs to the ribF family. | 0.627 |