STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APY04_2285Glutathione reductase; Maintains high levels of reduced glutathione. (461 aa)    
Predicted Functional Partners:
APY04_2619
Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 0.999
APY04_1934
Thioredoxin domain-containing protein EC-YbbN; COG3118.
   
 
 0.972
gshB
Glutathione synthetase; Belongs to the prokaryotic GSH synthase family.
     
 0.935
pdhA
Pyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.921
APY04_0031
Glutathione S-transferase.
     
 0.915
APY04_3379
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
    
 0.914
APY04_0723
2-oxoglutarate dehydrogenase E1 component.
  
 0.913
APY04_0864
Glutathione S-transferase family protein.
   
 
 0.909
APY04_2620
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 
  0.904
APY04_1396
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 
  0.902
Your Current Organism:
Hyphomicrobium sulfonivorans
NCBI taxonomy Id: 121290
Other names: ATCC BAA-113, DSM 13863, H. sulfonivorans, Hyphomicrobium sp. S1, Hyphomicrobium sulfonivorans Borodina et al. 2002, strain S1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.