STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APY04_2395Hypothetical protein. (338 aa)    
Predicted Functional Partners:
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.721
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
    
  0.699
APY04_1301
Hypothetical protein.
  
     0.608
APY04_3503
Hypothetical protein; Similar to TadZ/CpaE, associated with Flp pilus assembly.
  
    0.514
APY04_2393
Hemolysin-type calcium-binding region.
  
    0.511
APY04_2554
Putative RNA methyltransferase, TrmH family.
  
     0.496
APY04_3504
Superfamily 1 helicase.
  
    0.449
rnpA
Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
   
    0.448
APY04_1220
Hypothetical protein.
  
     0.406
APY04_2555
Hypothetical protein.
  
     0.403
Your Current Organism:
Hyphomicrobium sulfonivorans
NCBI taxonomy Id: 121290
Other names: ATCC BAA-113, DSM 13863, H. sulfonivorans, Hyphomicrobium sp. S1, Hyphomicrobium sulfonivorans Borodina et al. 2002, strain S1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.