STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APY04_3203Ribonuclease E inhibitor RraA; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions. (163 aa)    
Predicted Functional Partners:
APY04_3204
Transcriptional regulator, XRE family.
       0.751
APY04_3202
Threonine dehydrogenase.
    
  0.697
APY04_1669
Hypothetical protein.
    
 0.656
APY04_0879
Arabinose 5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily.
    
  0.630
APY04_3205
Isocitrate lyase.
 
    0.620
APY04_0595
Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
    
  0.558
APY04_1270
Oxalate decarboxylase.
    
  0.535
APY04_2312
Muconate cycloisomerase.
  
 
 0.478
APY04_0465
Transcriptional regulator, TetR family.
  
     0.465
APY04_0456
ATP-dependent RNA helicase RhlE.
    
 
 0.453
Your Current Organism:
Hyphomicrobium sulfonivorans
NCBI taxonomy Id: 121290
Other names: ATCC BAA-113, DSM 13863, H. sulfonivorans, Hyphomicrobium sp. S1, Hyphomicrobium sulfonivorans Borodina et al. 2002, strain S1
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