STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metE5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (778 aa)    
Predicted Functional Partners:
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
 
 
 0.981
APY04_2053
S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family.
  
 0.980
APY04_2219
5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
 
 0.978
APY04_3102
O-succinylhomoserine sulfhydrylase.
  
 
 0.930
APY04_2218
5-methyltetrahydrofolate--homocysteine methyltransferase.
  
 
 0.914
metZ
O-acetylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
  
 
 0.902
APY04_3066
Cystathionine beta-lyase.
  
 
 0.902
APY04_1794
Homoserine dehydrogenase.
   
 
 0.874
APY04_0131
Cysteine synthase.
     
 0.800
APY04_2087
Cysteine synthase.
     
 0.797
Your Current Organism:
Hyphomicrobium sulfonivorans
NCBI taxonomy Id: 121290
Other names: ATCC BAA-113, DSM 13863, H. sulfonivorans, Hyphomicrobium sp. S1, Hyphomicrobium sulfonivorans Borodina et al. 2002, strain S1
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