STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APY04_3428Dihydropteroate synthase. (361 aa)    
Predicted Functional Partners:
APY04_1579
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase.
 
 0.999
APY04_1224
Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family.
 
 0.997
APY04_1566
Dihydroneopterin aldolase; Delta 1-pyrroline-5-carboxylate synthetase.
 
 
 0.990
APY04_2327
Para-aminobenzoate synthase, aminase component; Aminodeoxychorismate lyase.
 
 
 0.969
folE-3
GTP cyclohydrolase I type 1.
 
 0.829
folE
GTP cyclohydrolase I type 1.
 
 0.828
folE-2
GTP cyclohydrolase I type 1.
 
 0.824
glmM
Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
 
  
 0.807
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  
 0.716
APY04_1333
Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone.
 
 
    0.696
Your Current Organism:
Hyphomicrobium sulfonivorans
NCBI taxonomy Id: 121290
Other names: ATCC BAA-113, DSM 13863, H. sulfonivorans, Hyphomicrobium sp. S1, Hyphomicrobium sulfonivorans Borodina et al. 2002, strain S1
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