STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALV40654.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (263 aa)    
Predicted Functional Partners:
gyrB
DNA topoisomerase IV subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.783
ALV43372.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.681
ALV40139.1
DNA topoisomerase IV subunit B; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.598
ALV43648.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.495
ALV41321.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.418
ALV43990.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.409
ALV42905.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.409
Your Current Organism:
Pseudarthrobacter sulfonivorans
NCBI taxonomy Id: 121292
Other names: ATCC BAA-112, Arthrobacter sp. ALL, Arthrobacter sulfonivorans, Arthrobacter sulfonivorans Borodina et al. 2002, DSM 14002, JCM 13520, P. sulfonivorans, Pseudarthrobacter sulfonivorans (Borodina et al. 2002) Busse 2016, strain ALL
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.