STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAC1Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family. (456 aa)    
Predicted Functional Partners:
Cob_v012581
Dynein heavy chain.
    
 0.995
Cob_v003436
Nuclear distribution protein nudE-like protein 1.
    
 
 0.947
DYNC1I2
Cytoplasmic dynein 1 intermediate chain 2.
   
 0.942
nudC
Nuclear movement protein nudC.
   
 0.939
ro-3
Dynactin, 150 kDa isoform.
    
 0.921
Cob_v006712
Dynein light chain.
    
 0.909
Cob_v009342
Uncharacterized protein.
    
 0.907
Cob_v006549
Uncharacterized protein.
     
 0.888
plg7
Putative phospholipase.
     
 0.888
DYNC1LI2
Cytoplasmic dynein 1 light intermediate chain 2.
   
 0.848
Your Current Organism:
Colletotrichum orbiculare
NCBI taxonomy Id: 1213857
Other names: C. orbiculare MAFF 240422, Colletotrichum orbiculare 104-T, Colletotrichum orbiculare MAFF 240422
Server load: low (14%) [HD]