A0A0G2HN93 protein (Diaporthe ampelina) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

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Score

A0A0G2HN93

Putative rrna-processing protein fcf2. (204 aa)

Predicted Functional Partners:

A0A0G2HKZ0

0.993

A0A0G2F6B5

0.992

A0A0G2FW01

0.992

A0A0G2FPW2

0.991

A0A0G2FU44

0.990

A0A0G2FVG0

0.989

A0A0G2FT96

0.988

A0A0G2H748

0.987

A0A0G2F9Y1

0.986

A0A0G2FJF2

0.985

Your Current Organism:

Diaporthe ampelina

NCBI taxonomy Id: 1214573
Other names: CBS 114016, D. ampelina, Diaporthe ampelina (Berk. & M.A. Curtis) R.R. Gomes, C. Glienke & Crous, Diaporthe neoviticola, Diaporthe sp. DU-2012e, Fusicoccum viticolum, Phoma ampelina, Phoma viticola, Phomopsis ampelina, Phomopsis sp. Pho06, Phomopsis sp. Pho07, Phomopsis sp. Pho10, Phomopsis sp. Pho16, Phomopsis sp. Pho18, Phomopsis sp. Pho24, Phomopsis sp. Pho25, Phomopsis sp. Pho26, Phomopsis sp. Pho28, Phomopsis sp. Pho32, Phomopsis sp. PhoCT1L, Phomopsis sp. taxon 2, Phomopsis viticola, STEU 2660

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A0G2F6B5	A0A0G2F9Y1	U3 small nucleolar RNA-associated protein 11; Involved in nucleolar processing of pre-18S ribosomal RNA.	Putative u3 small nucleolar rna-associated protein 6.	0.987
A0A0G2F6B5	A0A0G2FJF2	U3 small nucleolar RNA-associated protein 11; Involved in nucleolar processing of pre-18S ribosomal RNA.	Putative utp21-domain-containing protein.	0.986
A0A0G2F6B5	A0A0G2FPW2	U3 small nucleolar RNA-associated protein 11; Involved in nucleolar processing of pre-18S ribosomal RNA.	Putative gtp binding protein bms1.	0.994
A0A0G2F6B5	A0A0G2FT96	U3 small nucleolar RNA-associated protein 11; Involved in nucleolar processing of pre-18S ribosomal RNA.	Putative u3 small nucleolar ribonucleoprotein imp4.	0.989
A0A0G2F6B5	A0A0G2FU44	U3 small nucleolar RNA-associated protein 11; Involved in nucleolar processing of pre-18S ribosomal RNA.	Putative sas10 utp3 c1d family protein.	0.996
A0A0G2F6B5	A0A0G2FVG0	U3 small nucleolar RNA-associated protein 11; Involved in nucleolar processing of pre-18S ribosomal RNA.	U3 small nucleolar ribonucleoprotein protein MPP10; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the MPP10 family.	0.992
A0A0G2F6B5	A0A0G2FW01	U3 small nucleolar RNA-associated protein 11; Involved in nucleolar processing of pre-18S ribosomal RNA.	Putative sas10 utp3 family protein.	0.999
A0A0G2F6B5	A0A0G2H748	U3 small nucleolar RNA-associated protein 11; Involved in nucleolar processing of pre-18S ribosomal RNA.	Putative small nucleolar ribonucleoprotein complex component.	0.991
A0A0G2F6B5	A0A0G2HKZ0	U3 small nucleolar RNA-associated protein 11; Involved in nucleolar processing of pre-18S ribosomal RNA.	Putative transcription factor aatf che-1.	0.994
A0A0G2F6B5	A0A0G2HN93	U3 small nucleolar RNA-associated protein 11; Involved in nucleolar processing of pre-18S ribosomal RNA.	Putative rrna-processing protein fcf2.	0.992
A0A0G2F9Y1	A0A0G2F6B5	Putative u3 small nucleolar rna-associated protein 6.	U3 small nucleolar RNA-associated protein 11; Involved in nucleolar processing of pre-18S ribosomal RNA.	0.987
A0A0G2F9Y1	A0A0G2FJF2	Putative u3 small nucleolar rna-associated protein 6.	Putative utp21-domain-containing protein.	0.999
A0A0G2F9Y1	A0A0G2FPW2	Putative u3 small nucleolar rna-associated protein 6.	Putative gtp binding protein bms1.	0.997
A0A0G2F9Y1	A0A0G2FT96	Putative u3 small nucleolar rna-associated protein 6.	Putative u3 small nucleolar ribonucleoprotein imp4.	0.991
A0A0G2F9Y1	A0A0G2FU44	Putative u3 small nucleolar rna-associated protein 6.	Putative sas10 utp3 c1d family protein.	0.997
A0A0G2F9Y1	A0A0G2FVG0	Putative u3 small nucleolar rna-associated protein 6.	U3 small nucleolar ribonucleoprotein protein MPP10; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the MPP10 family.	0.995
A0A0G2F9Y1	A0A0G2FW01	Putative u3 small nucleolar rna-associated protein 6.	Putative sas10 utp3 family protein.	0.998
A0A0G2F9Y1	A0A0G2H748	Putative u3 small nucleolar rna-associated protein 6.	Putative small nucleolar ribonucleoprotein complex component.	0.998
A0A0G2F9Y1	A0A0G2HKZ0	Putative u3 small nucleolar rna-associated protein 6.	Putative transcription factor aatf che-1.	0.996
A0A0G2F9Y1	A0A0G2HN93	Putative u3 small nucleolar rna-associated protein 6.	Putative rrna-processing protein fcf2.	0.986

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Network Stats

number of nodes:

11

number of edges:

34

average node degree:

6.18

avg. local clustering coefficient:

0.789

expected number of edges:

17

PPI enrichment p-value:

0.000128

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
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Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000294

Nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay

3 of 8

2.77

2.14

0.00012

GO:0001682

tRNA 5-leader removal

3 of 10

2.67

2.13

0.00012

GO:0090502

RNA phosphodiester bond hydrolysis, endonucleolytic

4 of 81

1.89

1.87

0.00012

GO:0034965

Intronic box C/D RNA processing

2 of 2

3.19

1.86

0.00044

GO:0090305

Nucleic acid phosphodiester bond hydrolysis

5 of 190

1.61

1.67

0.00012

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004526

Ribonuclease P activity

3 of 9

2.72

2.25

7.28e-05

GO:0004519

Endonuclease activity

4 of 82

1.88

1.89

0.00011

GO:0033204

Ribonuclease P RNA binding

2 of 2

3.19

1.77

0.00063

GO:0140640

Catalytic activity, acting on a nucleic acid

5 of 445

1.24

1.07

0.0010

GO:0003723

RNA binding

5 of 624

1.1

0.83

0.0035

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000172

Ribonuclease MRP complex

5 of 14

2.75

4.99

3.67e-10

GO:0005655

Nucleolar ribonuclease P complex

4 of 10

2.79

4.14

1.94e-08

GO:0140513

Nuclear protein-containing complex

5 of 659

1.07

0.83

0.0031

GO:0005634

Nucleus

7 of 2657

0.61

0.39

0.0283

GO:0032991

Protein-containing complex

6 of 1995

0.67

0.39

0.0448

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:6727

Nucleolar ribonuclease P complex

5 of 10

2.89

5.13

2.74e-10

CL:6731

Nucleolar ribonuclease P complex

4 of 5

3.1

4.39

9.38e-09

CL:6442

Mixed, incl. PCNA-Dependent Long Patch Base Excision Repair, and Endoribonuclease complex

6 of 158

1.77

2.73

1.90e-07

CL:14018

2-deoxyribonucleotide biosynthetic process, and Queuine tRNA-ribosyltransferase activity

3 of 13

2.56

2.37

3.82e-05

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03008

Ribosome biogenesis in eukaryotes

5 of 113

1.84

2.61

9.79e-07

map00240

Pyrimidine metabolism

3 of 78

1.78

1.47

0.00084

map03013

RNA transport

4 of 193

1.51

1.41

0.00040

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-499943

Interconversion of nucleotide di- and triphosphates

3 of 29

2.21

1.59

0.00093

MAP-15869

Metabolism of nucleotides

3 of 104

1.65

0.86

0.0181

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0030677

Ribonuclease P complex

4 of 18

2.54

3.25

6.77e-07

GOCC:0005655

Nucleolar ribonuclease P complex

3 of 14

2.52

2.39

3.37e-05

GOCC:0000172

Ribonuclease MRP complex

3 of 15

2.49

2.38

3.37e-05

GOCC:0043505

CENP-A containing nucleosome

2 of 2

3.19

1.97

0.00028

GOCC:1990904

Ribonucleoprotein complex

5 of 473

1.22

1.1

0.00056

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0819

tRNA processing

2 of 17

2.26

0.97

0.0160

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