STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A0G2I441Putative histone acetylation protein 2. (256 aa)    
Predicted Functional Partners:
A0A0G2FJU7
Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.
   
 0.970
A0A0G2FZM7
Putative wd domain-containing protein.
   
 0.970
A0A0G2FYE1
Putative rna polymerase ii elongator complex subunit.
   
 
 0.803
NCS6
Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.
   
 
 0.702
A0A0G2HI19
Uncharacterized protein; Belongs to the synaptobrevin family.
 
  
  0.652
A0A0G2F9Y1
Putative u3 small nucleolar rna-associated protein 6.
   
 
 0.626
A0A0G2FPX2
Putative nucleolar gtp-binding protein 2.
   
  0.616
uba4
Adenylyltransferase and sulfurtransferase uba4; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and MOCS2A. Its N-terminus first activates urm1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...]
   
 
 0.604
A0A0G2FR40
Putative wd repeat-containing protein.
   
  0.554
A0A0G2FXZ6
Putative pre-rrna-processing protein ipi1.
   
 0.534
Your Current Organism:
Diaporthe ampelina
NCBI taxonomy Id: 1214573
Other names: CBS 114016, D. ampelina, Diaporthe ampelina (Berk. & M.A. Curtis) R.R. Gomes, C. Glienke & Crous, Diaporthe neoviticola, Diaporthe sp. DU-2012e, Fusicoccum viticolum, Phoma ampelina, Phoma viticola, Phomopsis ampelina, Phomopsis sp. Pho06, Phomopsis sp. Pho07, Phomopsis sp. Pho10, Phomopsis sp. Pho16, Phomopsis sp. Pho18, Phomopsis sp. Pho24, Phomopsis sp. Pho25, Phomopsis sp. Pho26, Phomopsis sp. Pho28, Phomopsis sp. Pho32, Phomopsis sp. PhoCT1L, Phomopsis sp. taxon 2, Phomopsis viticola, STEU 2660
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